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1
Blood brain barrier opening is not just blood-brain barrier opening.血脑屏障开放并非仅仅是血脑屏障的打开。
J Transl Med. 2024 Jul 15;22(1):660. doi: 10.1186/s12967-024-05431-0.
2
Blood-brain barrier opening to large molecules does not imply blood-brain barrier opening to small ions.血脑屏障对大分子的开放并不意味着对小离子的开放。
Neurobiol Dis. 2013 Apr;52:204-18. doi: 10.1016/j.nbd.2012.12.007. Epub 2013 Jan 3.
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Safety evaluation of frequent application of microbubble-enhanced focused ultrasound blood-brain-barrier opening.微泡增强聚焦超声频繁应用于血脑屏障开放的安全性评估。
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Permeability dependence study of the focused ultrasound-induced blood-brain barrier opening at distinct pressures and microbubble diameters using DCE-MRI.利用 DCE-MRI 研究不同压力和微泡直径下聚焦超声诱导的血脑屏障开放的通透性依赖性。
Magn Reson Med. 2011 Sep;66(3):821-30. doi: 10.1002/mrm.22848. Epub 2011 Apr 4.
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A Porcine Model of Transvertebral Ultrasound and Microbubble-Mediated Blood-Spinal Cord Barrier Opening.经皮椎体超声联合微泡介导血脊髓屏障开放的猪模型
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Claudin-5 binder enhances focused ultrasound-mediated opening in an blood-brain barrier model.Claudin-5 结合剂增强了血脑屏障模型中的聚焦超声介导的开放。
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Opening the blood-brain barrier by focused ultrasound.通过聚焦超声打开血脑屏障。
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Establishing sheep as an experimental species to validate ultrasound-mediated blood-brain barrier opening for potential therapeutic interventions.建立绵羊作为实验动物模型,验证超声介导的血脑屏障开放用于潜在的治疗干预。
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Modeling hyperosmotic blood-brain barrier opening within human tissue-engineered in vitro brain microvessels.在人组织工程体外脑微血管中模拟高渗性血脑屏障开放。
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Reversible opening of the blood-brain barrier by claudin-5-binding variants of Clostridium perfringens enterotoxin's claudin-binding domain.Claudin-5 结合变异型产气荚膜梭菌肠毒素的闭合蛋白结合域可逆打开血脑屏障。
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本文引用的文献

1
A study combining microbubble-mediated focused ultrasound and radiation therapy in the healthy rat brain and a F98 glioma model.一项在健康大鼠脑和 F98 神经胶质瘤模型中联合应用微泡介导的聚焦超声和放射治疗的研究。
Sci Rep. 2024 Feb 28;14(1):4831. doi: 10.1038/s41598-024-55442-6.
2
Focused ultrasound combined with radiotherapy for malignant brain tumor: a preclinical and clinical study.聚焦超声联合放疗治疗恶性脑肿瘤:临床前和临床研究。
J Neurooncol. 2023 Dec;165(3):535-545. doi: 10.1007/s11060-023-04517-x. Epub 2023 Dec 7.
3
Role of Acid Sphingomyelinase and Ceramide in Mechano-Acoustic Enhancement of Tumor Radiation Responses.酸鞘磷脂酶和神经酰胺在机械声增强肿瘤放射反应中的作用。
J Natl Cancer Inst. 2018 Sep 1;110(9):1009-1018. doi: 10.1093/jnci/djy011.
4
Bioeffects of ultrasound-stimulated microbubbles on endothelial cells: gene expression changes associated with radiation enhancement in vitro.超声刺激微泡对血管内皮细胞的生物效应:体外辐射增强相关的基因表达变化。
Ultrasound Med Biol. 2012 Nov;38(11):1958-69. doi: 10.1016/j.ultrasmedbio.2012.07.009. Epub 2012 Sep 12.
5
Engaging the vascular component of the tumor response.激活肿瘤反应的血管成分。
Cancer Cell. 2005 Aug;8(2):89-91. doi: 10.1016/j.ccr.2005.07.014.

Blood brain barrier opening is not just blood-brain barrier opening.

作者信息

Sharma Deepa, Czarnota Gregory J

机构信息

Sunnybrook Research Institute and Sunnybrook Health Sciences Centre, Ontario, Canada.

出版信息

J Transl Med. 2024 Jul 15;22(1):660. doi: 10.1186/s12967-024-05431-0.

DOI:10.1186/s12967-024-05431-0
PMID:39010143
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11247840/
Abstract
摘要