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黑人成年人中的HIV暴露前预防覆盖情况:对不平等、差异及影响的概念分析

HIV PrEP Coverage Among Black Adults: A Concept Analysis of the Inequities, Disparities, and Implications.

作者信息

Odii Ikenna Obasi, Vance David E, Patrician Patricia A, Dick Tracey K, Wise Jenni, Corcoran Jessica L, Elopre Latesha, Lambert Crystal Chapman

机构信息

School of Nursing, University of Alabama at Birmingham, Birmingham, Alabama, USA.

Division of Infectious Disease, University of Alabama at Birmingham, Birmingham, Alabama, USA.

出版信息

Health Equity. 2024 May 15;8(1):314-324. doi: 10.1089/heq.2023.0250. eCollection 2024.

Abstract

BACKGROUND

Significant racial disparities exist in HIV pre-exposure prophylaxis (PrEP) coverage in the United States (U.S), with Black individuals experiencing seven times higher new HIV infection rates compared to their White counterparts. Despite being the highest priority population at risk for HIV, Black adults have the lowest PrEP coverage, impacting the overall progress toward meeting the ending the HIV epidemic (EHE) goals in the U.S.

METHODS

Utilizing the Walker and Avant method, this concept analysis examined existing literature and U.S. Centers for Disease Control and Prevention resources to explore HIV PrEP coverage.

RESULTS

Findings highlighted a lack of clarity in the concept, resulting in four operational definitions. To address this ambiguity, a conceptual definition of HIV PrEP coverage was proposed, focusing on equitable access to PrEP medication among sexually active individuals aged 18-64 years, particularly those traditionally underserved and would benefit from PrEP. This inclusive definition aims to align with the dynamics of sexual behavior in racial minority groups. Key attributes of this conceptual definition include estimates of PrEP use, access, need, cost, side effects, frequency of HIV testing, and self-efficacy. Antecedents entail HIV status, testing behaviors, transmission risks, and communication with health care providers. Consequences involve perceptions of risk, screening routines, provider biases, stigma, and potential HIV transmission reduction.

CONCLUSION

Analyzing HIV PrEP coverage offers useful insights into social and structural factors exacerbating health inequities in the field of HIV prevention and control. This concept analysis underscores the importance of unified sexual health communication, diverse approaches to PrEP access for racial minorities, and improved sexual health policies for Black adults. Moreover, understanding and advocating for equity in HIV PrEP coverage is crucial for addressing the existing racial disparities and achieving the EHE objectives in the U.S.

摘要

背景

在美国,艾滋病毒暴露前预防(PrEP)的覆盖情况存在显著的种族差异,黑人个体的新增艾滋病毒感染率是白人的七倍。尽管黑人成年人是艾滋病毒高危的首要人群,但他们的PrEP覆盖率却最低,这影响了美国在实现终结艾滋病毒流行(EHE)目标方面的整体进展。

方法

本概念分析采用沃克和阿万特的方法,研究了现有文献以及美国疾病控制与预防中心的资源,以探讨艾滋病毒PrEP的覆盖情况。

结果

研究结果凸显了该概念缺乏清晰度,从而产生了四种操作性定义。为解决这一模糊性问题,提出了艾滋病毒PrEP覆盖的概念性定义,重点关注18至64岁性活跃个体,尤其是那些传统上未得到充分服务且能从PrEP中受益的个体公平获取PrEP药物的情况。这一包容性定义旨在与少数族裔群体的性行为动态相契合。这一概念性定义的关键属性包括PrEP的使用、获取、需求、成本、副作用、艾滋病毒检测频率和自我效能的估计。先决条件包括艾滋病毒感染状况、检测行为、传播风险以及与医疗服务提供者的沟通。后果涉及风险认知、筛查程序、提供者偏见、耻辱感以及潜在的艾滋病毒传播减少。

结论

分析艾滋病毒PrEP覆盖情况有助于深入了解在艾滋病毒预防和控制领域加剧健康不平等的社会和结构因素。这一概念分析强调了统一的性健康沟通、针对少数族裔的多样化PrEP获取途径以及改善黑人成年人的性健康政策的重要性。此外,理解并倡导艾滋病毒PrEP覆盖的公平性对于解决现有的种族差异以及实现美国的EHE目标至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/812c/11249128/28f1e5632b39/heq.2023.0250_figure1.jpg

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