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增强慢性阻塞性肺疾病患者的能力:优化吸入技术。

Empowering the Patient With Chronic Obstructive Pulmonary Disease: Optimizing Inhalation Technique.

作者信息

Castro Sofia, Moura Jorge, Dias Filipa, Magalhães Diogo, Vasconcelos Inês, Abreu António, Rio Mariana, Sousa Inês, Corral Maria, Ferreira Edmundo

机构信息

Porto Centro Family Health Unit, Local Health Unit São João, Porto, PRT.

出版信息

Cureus. 2025 Jan 6;17(1):e77019. doi: 10.7759/cureus.77019. eCollection 2025 Jan.

DOI:10.7759/cureus.77019
PMID:39912034
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11798567/
Abstract

Introduction Chronic obstructive pulmonary disease (COPD) is a heterogeneous lung disease characterized by chronic respiratory symptoms. Validated tools such as the modified Medical Research Council (mMRC) and COPD Assessment Test (CAT) questionnaires are commonly used to assess these symptoms. In Portugal, it is estimated that COPD affects approximately 14.2% of individuals aged 40 and over. Compliance with inhalation therapy remains a significant challenge. Inconsistent and incorrect use of inhalers contributes to suboptimal disease control and deteriorates the patients' quality of life. Regular evaluations provide a valuable opportunity to monitor symptom progression, assess therapeutic compliance, and understand patients' beliefs and expectations about their treatment. Objective The primary aim of this study was to enhance the correct use of inhalers at the Porto Centro Family Health Unit by at least 20% of the COPD patients included. The secondary goal was to evaluate how inhaler therapy compliance and proper technique impact the symptomatic control of COPD, as measured by the mMRC and CAT scales. Methods A prospective observational cohort study was developed, with an intervention component. Data were gathered through random sampling of patients diagnosed with COPD. Participants were invited for an initial evaluation, where they were educated about the disease, instructed on the correct inhalation technique, and assessed for both symptom severity and inhaler technique. They were then re-assessed at a follow-up visit. Descriptive and analytical statistical methods were applied to compare and interpret the results. This study was approved by the Ethics Committee of Local Health Unit São João. Results A total of 60 patients were randomly selected for participation. After applying exclusion criteria, refusal to participate, and missed appointments, 19 participants completed the study. Approximately two-thirds of the patients initially failed at least one step of the inhalation technique. Following the intervention, 79% of the patients were able to correctly perform all steps, reflecting a 47% improvement. Symptom assessment using the CAT questionnaire showed scores ranging from 8 to 21 (median = 8) at the first visit, which improved to a range of 0 to 21 (median = 4) at the follow-up visit. In terms of mMRC scores, only one patient showed a worsening of dyspnea classification, three patients improved, and the remaining patients had stable classifications. Discussion Inhalation therapy is crucial for effective COPD management. Following the intervention, a 47% improvement in inhaler technique was observed, which could lead to better disease control, fewer hospital admissions, and an enhanced quality of life. Although there are limitations such as the small sample size, the study demonstrated symptom improvement between the first and second visits, potentially indicating improved disease management. Conclusions This study highlights the impact that a focused intervention in managing COPD can have on improving patient outcomes and quality of life.

摘要

引言

慢性阻塞性肺疾病(COPD)是一种以慢性呼吸道症状为特征的异质性肺部疾病。诸如改良医学研究委员会(mMRC)问卷和慢性阻塞性肺疾病评估测试(CAT)问卷等经过验证的工具通常用于评估这些症状。在葡萄牙,据估计慢性阻塞性肺疾病影响约14.2%的40岁及以上人群。吸入疗法的依从性仍然是一项重大挑战。吸入器使用不一致和不正确会导致疾病控制不佳,并使患者生活质量下降。定期评估为监测症状进展、评估治疗依从性以及了解患者对其治疗的信念和期望提供了宝贵机会。

目的

本研究的主要目的是使波尔图中心家庭健康单元至少20%的慢性阻塞性肺疾病患者正确使用吸入器。次要目标是评估吸入器治疗依从性和正确技术如何影响慢性阻塞性肺疾病的症状控制,采用mMRC和CAT量表进行测量。

方法

开展了一项前瞻性观察队列研究,并设有干预部分。通过对诊断为慢性阻塞性肺疾病的患者进行随机抽样收集数据。邀请参与者进行初始评估,在评估中对他们进行疾病教育、指导正确的吸入技术,并评估症状严重程度和吸入器技术。然后在随访时对他们进行重新评估。应用描述性和分析性统计方法来比较和解释结果。本研究获得了当地圣若昂健康单元伦理委员会的批准。

结果

总共随机选择60名患者参与。在应用排除标准、拒绝参与和失约后,19名参与者完成了研究。大约三分之二的患者最初在吸入技术的至少一个步骤上失败。干预后,79%的患者能够正确完成所有步骤,显示出47%的改善。使用CAT问卷进行的症状评估显示,首次就诊时分数范围为8至21(中位数 = 8),随访时改善为0至21(中位数 = 4)。就mMRC分数而言,只有一名患者的呼吸困难分级恶化,三名患者改善,其余患者分级稳定。

讨论

吸入疗法对于慢性阻塞性肺疾病的有效管理至关重要。干预后,观察到吸入器技术有47%的改善,这可能导致更好的疾病控制、更少的住院次数以及更高的生活质量。尽管存在样本量小等局限性,但该研究表明首次就诊和第二次就诊之间症状有所改善,这可能表明疾病管理得到了改善。

结论

本研究强调了针对慢性阻塞性肺疾病管理的重点干预对改善患者结局和生活质量的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47d8/11798567/ebbb8c3dae06/cureus-0017-00000077019-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47d8/11798567/ba0e2f3da92b/cureus-0017-00000077019-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47d8/11798567/6b75cf92454c/cureus-0017-00000077019-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47d8/11798567/73f571ebec93/cureus-0017-00000077019-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47d8/11798567/ebbb8c3dae06/cureus-0017-00000077019-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47d8/11798567/ba0e2f3da92b/cureus-0017-00000077019-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47d8/11798567/6b75cf92454c/cureus-0017-00000077019-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47d8/11798567/73f571ebec93/cureus-0017-00000077019-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47d8/11798567/ebbb8c3dae06/cureus-0017-00000077019-i04.jpg

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The modified Medical Research Council scale misclassifies exertional breathlessness among people referred for exercise testing.
改良的医学研究委员会量表会将转诊进行运动测试的人群中的运动性呼吸困难误分类。
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