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根据单光子发射计算机断层扫描成像结果进行腰椎小关节腔内注射皮质类固醇的短期疗效

Short-Term Outcomes of Intraarticular Corticosteroid Injection into the Lumbar Facet Joint According to the Findings of Single-Photon Emission Computed Tomography Imaging.

作者信息

Chang Min Cheol, Yang Seoyon

机构信息

Department of Rehabilitation Medicine, College of Medicine, Yeungnam University, Daegu, Republic of Korea.

Department of Rehabilitation Medicine, School of Medicine, Ewha Woman's University Seoul Hospital, Seoul, Republic of Korea.

出版信息

J Pain Res. 2024 Jul 9;17:2357-2362. doi: 10.2147/JPR.S467549. eCollection 2024.

DOI:10.2147/JPR.S467549
PMID:39011278
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11247125/
Abstract

OBJECTIVE

Bone single-photon emission computed tomography (SPECT) preferentially localizes areas exhibiting greater bone remodeling and enhanced perfusion, which helps identify areas of pain and inflammation in the lumbar facet joints (LFJs). Herein, we investigated the treatment outcome of intraarticular (IA) corticosteroid injection in patients with LFJ-origin lower back pain (LBP) depending on the presence of increased LFJ uptake on bone SPECT.

METHODS

We retrospectively recruited 38 patients with LFJ-origin LBP. Of the 38 patients, 22 patients showed increased uptake on bone SPECT (SPECT+ group), and 16 patients did not show increased uptake on bone SPECT (SPECT- group). A numeric rating scale (NRS) was used to assess pain reduction 1 month after treatment with a corticosteroid injection. Treatment was considered successful when the posttreatment NRS score was ≥50% lower than the pretreatment NRS score.

RESULTS

The NRS scores of the SPECT+ group at the 1-month follow-up were significantly lower than those of the SPECT- group. Additionally, the degree of change in the NRS scores was larger in the SPECT+ group than that in the SPECT- group. In addition, 18 of the 22 patients (81.8%) in the SPECT+ group underwent successful treatment. Eight of the 16 patients (50%) in the SPECT- group underwent successful treatment. The ratio of successful treatment was significantly higher in the SPECT+ group than in the SPECT- group.

DISCUSSION

Bone SPECT could help predict the therapeutic outcome after IA LFJ corticosteroid injection and determine the treatment plan for patients with LFJ-origin LBP.

摘要

目的

骨单光子发射计算机断层扫描(SPECT)可优先定位显示出更大骨重塑和增强灌注的区域,这有助于识别腰椎小关节(LFJ)的疼痛和炎症区域。在此,我们根据骨SPECT上LFJ摄取增加的情况,研究了关节内(IA)注射皮质类固醇对LFJ源性下腰痛(LBP)患者的治疗效果。

方法

我们回顾性招募了38例LFJ源性LBP患者。在这38例患者中,22例患者在骨SPECT上显示摄取增加(SPECT+组),16例患者在骨SPECT上未显示摄取增加(SPECT-组)。使用数字评分量表(NRS)评估皮质类固醇注射治疗1个月后的疼痛减轻情况。当治疗后NRS评分比治疗前NRS评分降低≥50%时,治疗被认为是成功的。

结果

SPECT+组在1个月随访时的NRS评分显著低于SPECT-组。此外,SPECT+组NRS评分的变化程度大于SPECT-组。此外,SPECT+组的22例患者中有18例(81.8%)治疗成功。SPECT-组的16例患者中有8例(50%)治疗成功。SPECT+组的成功治疗率显著高于SPECT-组。

讨论

骨SPECT有助于预测IA LFJ皮质类固醇注射后的治疗效果,并确定LFJ源性LBP患者的治疗方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/300d/11247125/3cd3fa619e4f/JPR-17-2357-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/300d/11247125/3cd3fa619e4f/JPR-17-2357-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/300d/11247125/3cd3fa619e4f/JPR-17-2357-g0001.jpg

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SPECT-CT as a Predictor of Pain Generators in Patients Undergoing Intra-Articular Injections for Chronic Neck and Back Pain.
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SPECT/CT in the Evaluation of Suspected Skeletal Pathology.SPECT/CT 评估疑似骨骼病变。
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