Gu Weigang, Tan Justin Ryan L, Jin Hangbin, Lou Qifeng, Tang Chuang, Cheung Ka Shing, Yang Jianfeng, Zhang Xiaofeng
Department of Gastroenterology Affiliated Hangzhou First People's Hospital Hangzhou China.
Department of Gastroenterology Chinese General Hospital and Medical Center Manila Philippines.
DEN Open. 2024 Jul 15;5(1):e408. doi: 10.1002/deo2.408. eCollection 2025 Apr.
Papillary adenomas, known precursors to papillary adenocarcinoma, warrant close monitoring due to their malignant potential. Historically, surgical resection represented the mainstay of treatment for papillary adenomas with intraductal extension. However, recent advancements in endoscopic techniques have facilitated the adoption of endoscopic papillectomy as a minimally invasive alternative in carefully selected cases. We report a case of an 82-year-old woman with a diagnosis of papillary adenoma exhibiting intraductal extension. This was managed with a novel endoscopic technique, balloon catheter-assisted endoscopic resection. Due to the obscured intraductal component of the papillary mass, a balloon occlusion catheter was deployed within the common bile duct and used as traction to facilitate endoscopic visualization of the mass. Endoscopic resection via papillectomy was subsequently performed. Histopathological examination of the resected specimen revealed a villous adenoma with high-grade dysplasia. Serial endoscopic ultrasound examinations with targeted papillary biopsies were performed to monitor for disease recurrence.
乳头状腺瘤是乳头状腺癌已知的前体,因其具有恶变潜能,需要密切监测。从历史上看,手术切除是导管内扩展型乳头状腺瘤的主要治疗方法。然而,内镜技术的最新进展促使在精心挑选的病例中采用内镜下乳头切除术作为一种微创替代方法。我们报告一例82岁女性诊断为导管内扩展型乳头状腺瘤的病例。该病例采用一种新型内镜技术——球囊导管辅助内镜切除术进行治疗。由于乳头状肿物的导管内部分难以看清,在胆总管内放置了一个球囊闭塞导管,并用作牵引以利于内镜下观察肿物。随后通过乳头切除术进行了内镜切除。切除标本的组织病理学检查显示为高级别异型增生的绒毛状腺瘤。进行了系列内镜超声检查并进行靶向乳头活检以监测疾病复发。