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环境与气候对生理衰老的影响:增强与年龄相关恢复力的综合途径

Environmental and Climate Impacts on Physiological Aging: Comprehensive Pathways to Enhanced Age-related Resilience.

作者信息

Zhang Chengmeng, Liu Shangjun, Chen Gong

机构信息

Institute of Population Research, Peking University, Beijing, China.

Oxford Institute of Population Ageing, Oxford, UK.

出版信息

Aging Dis. 2024 Jun 27;16(3):1218-1224. doi: 10.14336/AD.2024.0478.

Abstract

This perspective article highlights the pressing necessity to focus on heterogeneity in organ-specific aging, emphasizing the influence of environmental and climate changes, as well as social interactions, on the aging process of individual organs. It explores innovative and integrative strategies tailored to the unique aging mechanisms of different organs, aiming to preserve their biological clocks. By emphasizing the importance of addressing organ-specific vulnerabilities, the article calls for transcending traditional pharmacological treatments and organ transplants. It proposes a comprehensive approach that combines environmental management, social support systems, and advanced technological interventions to improve the well-being and longevity of aging populations.

摘要

这篇观点文章强调了关注器官特异性衰老异质性的迫切必要性,强调环境和气候变化以及社会互动对各个器官衰老过程的影响。它探索了针对不同器官独特衰老机制的创新和综合策略,旨在维持其生物钟。通过强调应对器官特异性脆弱性的重要性,文章呼吁超越传统的药物治疗和器官移植。它提出了一种综合方法,将环境管理、社会支持系统和先进技术干预相结合,以改善老龄人口的健康和寿命。

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