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Mode of action of delta-9-tetrahydrocannabinol on hypothalamo-pituitary function in adult female rats.

作者信息

Chakravarty I, Shah P G, Sheth A R, Ghosh J J

出版信息

J Reprod Fertil. 1979 Sep;57(1):113-5. doi: 10.1530/jrf.0.0570113.

Abstract

Administration of delta-9-tetrahydrocannabinol (delta 9-THC) to pro-oestrous rats (5 mg/kg and 10 mg/kg, i.p. for 10 days) decreased the hypothalamic LH-RH content. Serum prolactin levels were reduced but serum LH and FSH and pituitary hormone content were similar to values in dioestrous rats. It is suggested that delta 9-THC acts primarily on the hypothalamus.

摘要

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