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表面消融手术后的压力诱导性基质角膜病变

Pressure-Induced Stromal Keratopathy after Surface Ablation Surgery.

作者信息

Guedes Jaime, Vilares-Morgado Rodrigo, Brazuna Rodrigo, Neto Alexandre Costa, Mora-Paez Denisse Josefina, Salomão Marcella Q, Faria-Correia Fernando, Ambrósio Renato

机构信息

Rio de Janeiro Corneal Tomography and Biomechanics Study Group, Rio de Janeiro, Brazil.

Department of Ophthalmology, Centro Hospitalar Universitário de S. João, Porto, Portugal.

出版信息

Case Rep Ophthalmol. 2024 Jul 1;15(1):532-541. doi: 10.1159/000539701. eCollection 2024 Jan-Dec.

Abstract

INTRODUCTION

The purpose of this clinical report was to describe an unprecedented case of bilateral pressure-induced stromal keratopathy (PISK) following corneal photorefractive keratectomy, associated with presumed herpetic keratitis, and to present tomographic and biomechanical findings before and after appropriate treatment.

CASE PRESENTATION

A 33-year-old male patient was referred to our clinic with suspected delayed corneal epithelial healing 3 weeks after an uncomplicated PRK. A central layer of corneal opacity with a presumed fluid-filled interface area was observed upon slit lamp biomicroscopy. Scheimpflug images from the Pentacam revealed a hyperreflective area beneath the central cornea. Scheimpflug-based corneal tomography, biomechanical assessment using the Pentacam AXL Wave, and the Corvis ST were conducted. Goldmann applanation tonometry measured 23/13 mm Hg, while noncontact tonometry intraocular pressure measured with the Corvis ST (Corvis ST IOPnct) was 40.5/43.5 mm Hg. Treatment with oral valacyclovir, combined with ocular hypotensive therapy, led to a significant reduction in IOP and improved corneal deformation parameters after 1 month.

CONCLUSION

Surgeons should be aware of the inaccuracy of Goldmann applanation tonometry in PISK, which can occur after LASIK or surface ablation.

摘要

引言

本临床报告旨在描述一例角膜屈光性角膜切削术后发生双侧压力性基质性角膜炎(PISK)的罕见病例,该病例与疑似疱疹性角膜炎相关,并展示适当治疗前后的断层扫描和生物力学检查结果。

病例介绍

一名33岁男性患者在接受无并发症的PRK术后3周因疑似角膜上皮愈合延迟被转诊至我院。裂隙灯生物显微镜检查发现中央角膜有一层混浊,推测其界面区域充满液体。Pentacam的Scheimpflug图像显示中央角膜下方有一个高反射区域。进行了基于Scheimpflug的角膜断层扫描、使用Pentacam AXL Wave的生物力学评估以及Corvis ST检查。Goldmann压平眼压计测量值为23/13 mmHg,而使用Corvis ST(Corvis ST IOPnct)测量的非接触眼压计眼压为40.5/43.5 mmHg。口服伐昔洛韦联合降眼压治疗1个月后,眼压显著降低,角膜变形参数得到改善。

结论

外科医生应意识到Goldmann压平眼压计在PISK中测量不准确,这种情况可发生在LASIK或表面消融术后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e3e/11250257/99ee2e6075ae/cop-2024-0015-0001-539701_F01.jpg

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