Wallingford Matthew P, Kelly Erin L, Herens Allison, Hanna Daniel, Hajjar Emily, Worster Brooke
Sidney Kimmel Medical School, Thomas Jefferson University, Philadelphia, PA, USA.
Department of Family and Community Medicine, Thomas Jefferson University, Philadelphia, PA, USA.
Med Cannabis Cannabinoids. 2024 Apr 16;7(1):80-85. doi: 10.1159/000538694. eCollection 2024 Jan-Dec.
Subjective improvement in gastrointestinal (GI) symptoms was assessed among patients using medical marijuana (MMJ).
Participants completed surveys at 0 days, 30 days, 6 months, and 12 months with questions about the severity of their GI symptoms on a scale from 1 (mild) to 3 (severe).
In each survey, participants reported a significant decrease in GI symptom severity when using MMJ versus when not using MMJ ( < 0.05). The most common self-reported side effects from using MMJ were increased appetite (12-21.4%), fatigue (6-16.7%), anxiety (4-11.9%), cough (4-11.9%), headache (6-7.9%), and dry mouth (4-7.1%).
In patients with chronic GI symptoms, MMJ may provide persistent symptom severity improvement. Limited product availability and mild to moderate side effects are factors to consider before trialing MMJ.
对使用医用大麻（MMJ）的患者的胃肠道（GI）症状主观改善情况进行了评估。
参与者在第0天、30天、6个月和12个月时完成调查问卷，问题涉及他们GI症状的严重程度，范围从1（轻度）到3（重度）。
在每次调查中，参与者报告使用MMJ时的GI症状严重程度比不使用MMJ时显著降低（<0.05）。使用MMJ最常见的自我报告副作用是食欲增加（12 - 21.4%）、疲劳（6 - 16.7%）、焦虑（4 - 11.9%）、咳嗽（4 - 11.9%）、头痛（6 - 7.9%）和口干（4 - 7.1%）。
在患有慢性GI症状的患者中，MMJ可能会持续改善症状严重程度。在试用MMJ之前，有限的产品供应以及轻度至中度的副作用是需要考虑的因素。
