Nover H, Botzenhart K
Zentralbl Bakteriol Mikrobiol Hyg B. 1985 Jun;181(1-2):71-80.
The multipurpose strain E. coli K12 343/113 allows the simultaneous detection of different DNA alterations such as base-pair changes, frameshifts and deletions. The investigations show the detection of mutagenic potency in the mixture which is called photochemical smog, produced by a flow reactor. Responsible for these effects were ozone and hydrocarbon-radicals, but not NOx, hydrocarbons (propene, isobutene, trans-2-butene) and peroxiacetylnitrate (PAN). In the given conditions these mutagenic substances are involved in DNA alterations like base-pair changes and deletions due to the amounts of colonies in the gal+-, MTR-, and arg+-system. No frameshifts could be detected in the nad+-system.
多功能菌株大肠杆菌K12 343/113可同时检测不同的DNA改变，如碱基对变化、移码突变和缺失。研究表明该多功能菌株能够检测流动反应器产生的名为光化学烟雾的混合物中的诱变效力。造成这些影响的是臭氧和碳氢化合物自由基，而非氮氧化物、碳氢化合物（丙烯、异丁烯、反-2-丁烯）和过氧乙酰硝酸酯（PAN）。在给定条件下，由于gal+、MTR-和arg+系统中的菌落数量，这些诱变物质会导致DNA发生碱基对变化和缺失等改变。在nad+系统中未检测到移码突变。
