Gebbers J O
Institut für Umweltmedizin Luzern.
Praxis (Bern 1994). 1996 Aug 13;85(33):971-7.
The extremely noxious gas ozone is of great contemporary interest, revealing also a fascinating history. Its tropospheric concentration has doubled in the past 100 years in the Northern Hemisphere. To answer some of the immediately important questions in relation to ozone, its biological effects and the mechanisms of action in the human organism are reviewed (first effects in man > 160 micrograms/m3, 0.08 ppm). We find out what questions are raised by animal studies to which epidemiologists might seek answers and that we are mostly not able to separate the adverse effects of ozone from those of other summer smog components travelling and interacting additively with it, namely NOx, aldehydes or peroxi-acetyl nitrate (PAN).
极具毒性的气体臭氧在当代备受关注,其历史也饶有趣味。在北半球,其对流层浓度在过去100年中增加了一倍。为回答一些与臭氧直接相关的重要问题,本文综述了臭氧在人体中的生物学效应及作用机制(人体的初始效应>160微克/立方米,0.08 ppm)。我们探究了动物研究提出的哪些问题是流行病学家可能寻求答案的,以及我们大多无法将臭氧的不利影响与其他夏季烟雾成分(即氮氧化物、醛类或过氧乙酰硝酸酯(PAN))的不利影响区分开来,这些成分与臭氧一起移动并产生累加相互作用。