Atlas E L, Donnelly K C, Giam C S, McFarland A R
Am Ind Hyg Assoc J. 1985 Sep;46(9):532-40. doi: 10.1080/15298668591395300.
Firefighters are routinely exposed to a wide variety of combustion products. To examine health-related aspects of their exposure to combustion products from specific sources, samples from oil fire plumes at a fireperson training facility were collected for chemical characterization of organic compounds and for Ames microbial mutagenesis biological testing. Chemical characterization of particulate and vapor-phase samples demonstrated the existence of a complex mixture of organics containing a series of alkanes, polynuclear aromatic hydrocarbons and other compounds. The Ames bioassay showed an average mutagenic response of 0.4 rev/microgram with most of the activity observed in strain TA98 with metabolic activation.
消防员经常接触各种各样的燃烧产物。为了研究他们接触特定来源燃烧产物对健康的影响,在一个消防员训练设施收集了油火羽流的样本,用于有机化合物的化学表征和艾姆斯微生物诱变生物测试。颗粒相和气相样本的化学表征表明存在一种复杂的有机混合物,其中包含一系列烷烃、多环芳烃和其他化合物。艾姆斯生物测定显示平均诱变反应为0.4 回复突变/微克,大部分活性在有代谢激活的TA98菌株中观察到。