Scher K S, Bernstein J M, Jones C W
Am Surg. 1985 Oct;51(10):577-9.
Bacterial adherence to vascular sutures was evaluated in vitro using radioactively labeled Staphylococcus aureus. The following suture materials were tested: polypropylene, silicone-treated braided polyester, and Teflon-treated braided polyester. Significantly fewer bacteria adhered to the monofilament polypropylene than either of the braided polyester sutures. There was no significant difference between silicone-treated and Teflon-treated polyester from the standpoint of bacterial adherence. Vascular sutures were evaluated in vivo using a mouse wound model. Sutures were tested with and without knots. When tested without knots, fewer bacteria were recovered from wounds containing polypropylene suture compared to either of the braided materials, although this apparent advantage did not prove to be statistically significant. When studied with knots, the differences among types of suture were much less marked and, again, not significant. The purported contribution of the monofilament structure of a suture to its infection resistance may have been overstated.
使用放射性标记的金黄色葡萄球菌在体外评估细菌对血管缝线的粘附情况。测试了以下缝线材料：聚丙烯、硅酮处理的编织聚酯和特氟龙处理的编织聚酯。与任何一种编织聚酯缝线相比，粘附到单丝聚丙烯上的细菌明显更少。从细菌粘附的角度来看，硅酮处理的聚酯和特氟龙处理的聚酯之间没有显著差异。使用小鼠伤口模型在体内评估血管缝线。对有结和无结的缝线进行了测试。当无结测试时，与任何一种编织材料相比，从含有聚丙烯缝线的伤口中回收的细菌更少，尽管这种明显的优势在统计学上并不显著。当有结研究时，缝线类型之间的差异要小得多，同样也不显著。缝线单丝结构对其抗感染性的所谓贡献可能被夸大了。
