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2021年蒙特利尔市重要非医护工作者中与新冠病毒检测、感染及疫苗接种相关的特征

Characteristics associated with SARS-CoV-2 testing, infection and vaccine uptake among essential non-healthcare workers in Montréal, 2021.

作者信息

Caya Chelsea, Menzies Dick, Papenburg Jesse, Yansouni Cedric, Campbell Jonathon

机构信息

Research Institute of the McGill University Health Centre, Montréal, QC.

McGill Interdisciplinary Initiative in Infection and Immunity, Montréal, QC.

出版信息

Can Commun Dis Rep. 2024 Jun 28;50(6):223-232. doi: 10.14745/ccdr.v50i06a05.

Abstract

BACKGROUND

Essential non-healthcare workers experienced higher rates of SARS-CoV-2 infection compared to non-essential workers.

OBJECTIVE

Identify characteristics associated with SARS-CoV-2 testing, infection and vaccine uptake among essential non-healthcare workers in Montréal, Québec.

METHODS

Secondary, cross-sectional analysis of data collected from participants prospectively recruited in two observational studies (first study, Onsite Testing Study, January-March 2021; second study, Self-Testing Study, July-October 2021) of essential non-healthcare workers in 2021. Logistic regression with generalized linear mixed models was used to explore characteristics associated with our outcomes (previous SARS-CoV-2 testing, exposure and vaccination).

RESULTS

Overall, 2,755 participants were included (first study, Onsite Testing Study, n=2,128; and second study, Self-Testing Study, n=627). A higher proportion of participants identified as male (n=1,601; 58%), non-White (n=1,527; 55%) and worked in the manufacturing/supplier sector (n=1,706; 62%). Relative to the first study, Onsite Testing Study, participants in the second study, Self-Testing Study, had higher odds (78% vs. 46%; aOR 4.1, 95% CI: 3.2-5.2) of previous SARS-CoV-2 testing and of testing positive prior to study enrolment (6.2% vs. 4.3%; aOR 1.7, 95% CI: 1.1-2.6). Individuals reporting recent SARS-CoV-2 exposure had higher odds of previous SARS-CoV-2 testing (aOR 4.0, 95% CI: 3.0-5.4), while older age (aOR 0.98, 95% CI: 0.98-0.99 per one-year increase) and being male (aOR 0.6, 95% CI: 0.5-0.7) were associated with lower odds of previous testing. Results were similar in stratified analyses. Participants from businesses with more than 50 employees had higher odds of having received a SARS-CoV-2 vaccine (91% vs. 80%; aOR 2.6, 95% CI: 1.4-4.8).

CONCLUSION

Consideration of individual and business characteristics associated with testing and vaccination programs for SARS-CoV-2 could improve equity, uptake and impact.

摘要

背景

与非必要工作者相比,必要非医护工作者感染严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的比例更高。

目的

确定魁北克省蒙特利尔市必要非医护工作者中与SARS-CoV-2检测、感染及疫苗接种相关的特征。

方法

对2021年从两项针对必要非医护工作者的观察性研究(第一项研究,现场检测研究,2021年1月至3月;第二项研究,自我检测研究,2021年7月至10月)中前瞻性招募的参与者收集的数据进行二次横断面分析。使用广义线性混合模型的逻辑回归来探索与我们的结果(既往SARS-CoV-2检测、暴露和疫苗接种)相关的特征。

结果

总体而言,共纳入2755名参与者(第一项研究,现场检测研究,n = 2128;第二项研究,自我检测研究,n = 627)。较高比例的参与者为男性(n = 1601;58%)、非白人(n = 1527;55%),且从事制造业/供应商行业(n = 1706;62%)。相对于第一项研究(现场检测研究),第二项研究(自我检测研究)中的参与者既往进行SARS-CoV-2检测的几率更高(78%对46%;调整后比值比[aOR]为4.1,95%置信区间[CI]:3.2 - 5.2),且在研究入组前检测呈阳性的几率更高(6.2%对4.3%;aOR为1.7,95% CI:1.1 - 2.6)。报告近期接触过SARS-CoV-2的个体既往进行SARS-CoV-2检测的几率更高(aOR为4.0,95% CI:3.0 - 5.4),而年龄较大(每增加一岁aOR为0.98,95% CI:0.98 - 0.99)和男性(aOR为0.6,95% CI:0.5 - 0.7)与既往检测几率较低相关。分层分析结果相似。来自员工超过50人的企业的参与者接种SARS-CoV-2疫苗的几率更高(91%对80%;aOR为2.6,95% CI:1.4 - 4.8)。

结论

考虑与SARS-CoV-2检测和疫苗接种计划相关的个体及企业特征,可能会提高公平性、接种率及效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/080e/11251738/af82de82f7b0/500605-f1.jpg

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