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采用FOLFOX-6方案治疗源于卵巢成熟性囊性畸胎瘤的黏液性肠腺癌——病例报告

Mucinous intestinal adenocarcinoma arising from mature cystic teratoma of the ovary treated with FOLFOX-6 - a case report.

作者信息

Bedoya-Ismodes Enrique, Portugal Karem, Carmona-Lozano Sandy, Dominguez-Gonzales Mirna, Torres Jaime, Juarez-Herrera Nestor

机构信息

Hospital Santa Rosa, Lima 15084, Perú.

Facultad de Medicina Humana, Universidad de San Martín de Porres, Lima, Perú.

出版信息

Ecancermedicalscience. 2024 Jun 4;18:1709. doi: 10.3332/ecancer.2024.1709. eCollection 2024.

DOI:10.3332/ecancer.2024.1709
PMID:39021545
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11254390/
Abstract

The malignant transformation of mature cystic teratomas during pregnancy is a rare occurrence in medical literature. In this case report, we present a remarkable instance of mucinous intestinal adenocarcinoma arising from a mature ovarian cystic teratoma diagnosed during pregnancy. This is among the few reports detailing the effective use of the FOLFOX 6 chemotherapy regimen for treating this type of intestinal cancer. Furthermore, we emphasize the immunohistochemical results that confirm the colorectal histological origin.

摘要

成熟囊性畸胎瘤在孕期发生恶变在医学文献中较为罕见。在本病例报告中,我们呈现了一例显著的病例,即孕期诊断出的成熟卵巢囊性畸胎瘤发生黏液性肠腺癌。这是少数详细描述FOLFOX 6化疗方案有效治疗此类肠道癌症的报告之一。此外,我们强调了证实结直肠组织学起源的免疫组化结果。

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J Natl Cancer Inst. 2024 Mar 7;116(3):356-369. doi: 10.1093/jnci/djad268.
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Preoperative Treatment of Locally Advanced Rectal Cancer.局部进展期直肠癌的术前治疗。
N Engl J Med. 2023 Jul 27;389(4):322-334. doi: 10.1056/NEJMoa2303269. Epub 2023 Jun 4.
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Malignant transformation of mature cystic teratoma of the ovary.卵巢成熟囊性畸胎瘤恶变。
J Obstet Gynaecol Res. 2022 Dec;48(12):3068-3076. doi: 10.1111/jog.15409. Epub 2022 Sep 2.
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The utility of PAX8 and SATB2 immunohistochemical stains in distinguishing ovarian mucinous neoplasms from colonic and appendiceal mucinous neoplasm.PAX8和SATB2免疫组化染色在鉴别卵巢黏液性肿瘤与结肠及阑尾黏液性肿瘤中的应用。
BMC Res Notes. 2019 Nov 26;12(1):770. doi: 10.1186/s13104-019-4816-9.
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Adnexal masses in pregnancy: An updated review.孕期附件包块:最新综述
Avicenna J Med. 2017 Oct-Dec;7(4):153-157. doi: 10.4103/ajm.AJM_22_17.
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Malignant transformation of ovarian mature cystic teratoma into squamous cell carcinoma: a Taiwanese Gynecologic Oncology Group (TGOG) study.卵巢成熟囊性畸胎瘤恶变为鳞状细胞癌:一项台湾妇科肿瘤学组(TGOG)的研究。
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Prognostic impact of lymphadenectomy in clinically early stage malignant germ cell tumour of the ovary.淋巴结切除术对临床早期卵巢恶性生殖细胞肿瘤的预后影响。
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