Erdil Duygu, Ozdemir Ozan, Manav Vildan
Department of Dermatology, University of Health Sciences Türkiye, Istanbul Training and Research Hospital, Istanbul, Türkiye.
Department of Otorhinolaryngology/Head and Neck Surgery, University of Health Sciences Türkiye, Istanbul Training and Research Hospital, Istanbul, Türkiye.
Sisli Etfal Hastan Tip Bul. 2024 Jun 28;58(2):226-232. doi: 10.14744/SEMB.2024.78785. eCollection 2024.
This study aimed to investigate the presence and severity of inferior turbinate hypertrophy (ITH) in patients with hypertrophic scars (HTS).
This case-control study was conducted with patients diagnosed with HTS during dermatologic examination and a control group without HTS. An otolaryngologist evaluated the presence and severity of inferior turbinate hypertrophy by anterior rhinoscopy.
ITH was more common in patients with HTS compared to the control group (64%, and 34%, respectively) (p=0.014). In the HTS group, 48% of patients had grade 2, and 16% had grade 3 ITH; in the control group, 24% had grade 2, and 10% had grade 3 ITH (p=0.046). Also, ITH was higher in patients who complained of pruritus or pain (83%, and 80%, respectively) in the HTS than in asymptomatic HTS patients (p=0.020).
A higher number of patients with HTS had ITH compared to the control group, especially those who reported pruritus or pain associated with scar. Given the limited understanding of the full pathogenesis and treatment of HTS and ITH, their association potentially provides new insights into these related conditions.
本研究旨在调查肥厚性瘢痕（HTS）患者下鼻甲肥大（ITH）的存在情况及严重程度。
本病例对照研究纳入了在皮肤科检查中被诊断为HTS的患者以及一个无HTS的对照组。一名耳鼻喉科医生通过前鼻镜检查评估下鼻甲肥大的存在情况及严重程度。
与对照组相比，HTS患者中ITH更为常见（分别为64%和34%）（p = 0.014）。在HTS组中，48%的患者为2级ITH，16%为3级ITH；在对照组中，24%为2级ITH，10%为3级ITH（p = 0.046）。此外，主诉HTS瘙痒或疼痛的患者中ITH发生率高于无症状HTS患者（分别为83%和80%）（p = 0.020）。
与对照组相比，HTS患者中ITH的人数更多，尤其是那些报告与瘢痕相关的瘙痒或疼痛的患者。鉴于对HTS和ITH的完整发病机制及治疗的了解有限，它们之间的关联可能为这些相关病症提供新的见解。
