Hamid Abdullgabbar M, Alshoabi Sultan A, Binnuhaid Abdulkhaleq A, Alsultan Kamal, Alzain Amel F, Aman Abdulmannan M
Radiology, Rush University Medical Center, Chicago, USA.
Diagnostic Radiology Technology, College of Applied Medical Sciences, Taibah University, Al-Madinah Al-Munawwarah, SAU.
Cureus. 2024 Jun 17;16(6):e62531. doi: 10.7759/cureus.62531. eCollection 2024 Jun.
Primary sclerosing cholangitis (PSC) is a rare chronic inflammatory disease in which multifocal fibrosis of bile ducts causes eventually narrowing and even blocking, forming multifocal strictures alternated to dilatations. Here, we reported an extremely rare case of PSC associated with ulcerative colitis (UC) and coexisting with cholangiocarcinoma in a 33-year-old male presented with right upper quadrant pain and dark urine. Liver function tests were deranged, and ERCP found a beaded cholangiography appearance due to multifocal bile duct strictures alternating with normal and dilated segments of the common hepatic duct and the intrahepatic bile ducts. We aim to document this typical case of PSC associated with UC and coexisted with cholangiocarcinoma to add the existing data on these rare pathologies.
原发性硬化性胆管炎（PSC）是一种罕见的慢性炎症性疾病，其中胆管的多灶性纤维化最终导致狭窄甚至阻塞，形成多灶性狭窄与扩张交替出现的情况。在此，我们报告了一例极其罕见的PSC病例，该病例与溃疡性结肠炎（UC）相关，并与胆管癌共存，患者为一名33岁男性，表现为右上腹疼痛和深色尿液。肝功能检查结果异常，内镜逆行胰胆管造影（ERCP）发现由于肝总管和肝内胆管的多灶性胆管狭窄与正常和扩张段交替出现，胆管造影呈串珠状外观。我们旨在记录这例与UC相关并与胆管癌共存的典型PSC病例，以补充这些罕见病理情况的现有数据。
