Department of Radiology, University of Pennsylvania Health System, 1 Silverstein, 3400 Spruce Street, Philadelphia, PA, USA.
Radiology and Medical Imaging, University of Virginia Health, 1215 Lee Street, Charlottesville, VA, USA.
Abdom Radiol (NY). 2023 Jan;48(1):136-150. doi: 10.1007/s00261-022-03655-6. Epub 2022 Sep 5.
Primary sclerosing cholangitis is a rare chronic inflammatory disease affecting the bile ducts, which can eventually result in bile duct strictures, cholestasis and cirrhosis. Patients are often asymptomatic but may present with clinical features of cholestasis. Imaging plays an important role in the diagnosis and management. This review covers the pathophysiology, clinical features, imaging findings as well as methods of surveillance and post-transplant appearance.
原发性硬化性胆管炎是一种罕见的慢性炎症性疾病，影响胆管，最终可导致胆管狭窄、胆汁淤积和肝硬化。患者通常无症状，但可能出现胆汁淤积的临床特征。影像学在诊断和治疗中起重要作用。本文综述了其病理生理学、临床特征、影像学表现以及监测和移植后表现的方法。
