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国际癌症研究机构(IARC)专论项目中化学品致癌性的数据。

Data on the carcinogenicity of chemicals in the IARC Monographs programme.

作者信息

Vainio H, Hemminki K, Wilbourn J

出版信息

Carcinogenesis. 1985 Nov;6(11):1653-65. doi: 10.1093/carcin/6.11.1653.

DOI:10.1093/carcin/6.11.1653
PMID:3902269
Abstract

Data were extracted from IARC Monographs volumes 1-38 on chemicals and exposures for which some data on carcinogenicity in humans, or sufficient evidence of carcinogenicity in experimental animals existed. In all, 288 chemicals, industrial processes and complex mixtures fulfilled these criteria. For 30 chemicals or mixtures of chemicals, and nine industrial processes, there was sufficient evidence of carcinogenicity in humans; and for 63 chemicals and mixtures of chemicals and for five industrial processes, there was evidence that these exposures were probably carcinogenic to humans. For 61 chemicals or groups of chemicals and six industrial processes or occupations, no evaluation of carcinogenicity to humans could be made. For 115 chemicals there is sufficient evidence of carcinogenicity to experimental animals, but no epidemiological data are available. Publications not earlier referred to on the carcinogenicity of these chemicals and exposures were found for approximately 70. A call is made for further information on these exposures with a view to updating the IARC Monographs.

摘要

数据取自国际癌症研究机构(IARC)《专论》第1 - 38卷,涉及那些在人类致癌性方面有一些数据,或在实验动物中有充分致癌证据的化学物质和暴露因素。总共有288种化学物质、工业过程和复杂混合物符合这些标准。对于30种化学物质或化学物质混合物以及9种工业过程,有充分的人类致癌证据;对于63种化学物质和化学物质混合物以及5种工业过程,有证据表明这些暴露因素可能对人类致癌。对于61种化学物质或化学物质组以及6种工业过程或职业,无法对其对人类的致癌性进行评估。对于115种化学物质,有充分的实验动物致癌证据,但尚无流行病学数据。大约发现了70篇此前未提及这些化学物质和暴露因素致癌性的出版物。呼吁提供有关这些暴露因素的更多信息,以便更新IARC《专论》。

相似文献

1
Data on the carcinogenicity of chemicals in the IARC Monographs programme.国际癌症研究机构(IARC)专论项目中化学品致癌性的数据。
Carcinogenesis. 1985 Nov;6(11):1653-65. doi: 10.1093/carcin/6.11.1653.
2
Chemicals and industrial processes associated with cancer in humans. IARC Monographs, Volumes 1 to 20.与人类癌症相关的化学物质和工业过程。《国际癌症研究机构专论》,第1至20卷。
IARC Monogr Eval Carcinog Risk Chem Hum Suppl. 1979 Sep(1):1-71.
3
An evaluation of chemicals and industrial processes associated with cancer in humans based on human and animal data: IARC Monographs Volumes 1 to 20.基于人类和动物数据对与人类癌症相关的化学品和工业过程的评估:《国际癌症研究机构专论》第1至20卷
Cancer Res. 1980 Jan;40(1):1-12.
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Target organs for carcinogenicity of chemicals and industrial exposures in humans: a review of results in the IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans.化学物质和职业暴露对人类致癌作用的靶器官:对国际癌症研究机构《化学物质对人类致癌风险评估专论》结果的综述
Cancer Res. 1984 May;44(5):2244-50.
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Carcinogenicity evaluations and ongoing studies: the IARC databases.致癌性评估与正在进行的研究:国际癌症研究机构数据库
Environ Health Perspect. 1991 Dec;96:5-9. doi: 10.1289/ehp.91965.
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IARC monographs, industry influence, and upgrading, downgrading, and under-grading chemicals: a personal point of view. International Agency for Research on Cancer.国际癌症研究机构专论、行业影响以及化学物质的升级、降级和评级不足:个人观点。国际癌症研究机构
Int J Occup Environ Health. 2002 Jul-Sep;8(3):249-70. doi: 10.1179/107735202800338795.
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[Identification of human carcinogenic risks in IARC monographs].[国际癌症研究机构专论中人类致癌风险的识别]
Bull Cancer. 1995;82(5):339-48.
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Evaluation of the carcinogenicity of chemicals: a review of the Monograph Program of the International Agency for Research on Cancer (1971 to 1977).化学品致癌性评估:国际癌症研究机构专论项目(1971年至1977年)综述
Cancer Res. 1978 Apr;38(4):877-85.
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The IARC program on the evaluation of the carcinogenic risk of chemicals to man.国际癌症研究机构关于评估化学物质对人类致癌风险的项目。
Ann N Y Acad Sci. 1976;271:396-409. doi: 10.1111/j.1749-6632.1976.tb23139.x.
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Concordance between sites of tumor development in humans and in experimental animals for 111 agents that are carcinogenic to humans.人类肿瘤发生部位与 111 种人类致癌剂在实验动物中的肿瘤发生部位的一致性。
J Toxicol Environ Health B Crit Rev. 2019;22(7-8):203-236. doi: 10.1080/10937404.2019.1642586.

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Chemicals and cancer in humans: first evidence in experimental animals.化学物质与人类癌症:实验动物中的首个证据。
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