Xin Jingjing, Wang Tongxing, Hou Bin, Lu Xuan, Han Ningxin, He Yanling, Zhang Dan, Wang Xiaoqi, Wei Cong, Jia Zhenhua
Graduate School, Hebei Medical University, Shijiazhuang, 050017, China.
State Key Laboratory for Innovation and Transformation of Luobing Theory, Shijiazhuang, 050035, China.
Heliyon. 2024 Jun 21;10(13):e33309. doi: 10.1016/j.heliyon.2024.e33309. eCollection 2024 Jul 15.
Cardiovascular diseases (CVDs) are one of the most significant diseases that pose a threat to human health. The innovative traditional Chinese medicine Tongxinluo Capsule, developed under the guidance of the theory of traditional Chinese medicine, has good clinical efficacy in various cardiovascular diseases, this medicine has effects such as blood protection, vascular protection, myocardial protection, stabilizing vulnerable plaques, and vasodilation. However, CVDs are a multifactorial disease, and their underlying mechanisms are not fully understood. Therefore, exploring the mechanism of action and clinical application of Tongxinluo Capsule in the treatment of various cardiovascular diseases is beneficial for exerting its therapeutic effect from multiple components, targets, and pathways. At the same time, it provides broader treatment ideas for other difficult to treat diseases in the cardiovascular event chain, and has significant theoretical and clinical significance for improving the treatment of cardiovascular diseases with traditional Chinese medicine.
心血管疾病（CVDs）是对人类健康构成威胁的最重要疾病之一。在中医理论指导下研发的创新中药通心络胶囊，在各种心血管疾病中具有良好的临床疗效，该药具有血液保护、血管保护、心肌保护、稳定易损斑块和血管舒张等作用。然而，心血管疾病是一种多因素疾病，其潜在机制尚未完全明了。因此，探索通心络胶囊治疗各种心血管疾病的作用机制和临床应用，有利于从多个成分、靶点和途径发挥其治疗作用。同时，为心血管事件链中其他难治性疾病提供更广泛的治疗思路，对提高中医药治疗心血管疾病具有重要的理论和临床意义。
