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一名1岁儿童颈椎原发性尤因肉瘤罕见病例:病例报告及文献综述

A rare case of Ewing's sarcoma primary of the cervical spine in a 1-year-old child: A case report and literature review.

作者信息

Shaker Kamar, Alomar Khaled, Wahoob Mohammed, Altabaa Kasem, Omran Mohammad, Marwa Ghassan

机构信息

Damascus University, University Pediatric Hospital, Syria.

Faculty of Medicine, Damascus University, Al Assad University Hospital, Syria.

出版信息

Int J Surg Case Rep. 2024 Sep;122:110020. doi: 10.1016/j.ijscr.2024.110020. Epub 2024 Jul 14.

DOI:10.1016/j.ijscr.2024.110020
PMID:39043091
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11318468/
Abstract

INTRODUCTION AND SIGNIFICANCE

Ewing sarcoma is a rare and malignant bone tumor that can primarily affect the cervical spine. Symptoms may not always be present, but muscle weakness is a critical indicator of disease progression and necessitates urgent surgical intervention to relieve pressure on the spinal cord.

CASE PRESENTATION

We present a case of a child who experienced sudden muscle weakness in the left upper limb. An MRI of the spine revealed a tumor in the cervical spine compressing the spinal cord. Urgent surgical intervention was performed, successfully removing most of the tumor. This was followed by complementary chemotherapy.

CLINICAL DISCUSSION

Tumors located in the cervical spine are challenging to treat due to their location. Urgent surgery may be crucial when muscle weakness is present. This case demonstrates a novel surgical approach through the spinous processes of the vertebrae, avoiding laminectomy and the need for spinal fixation, which can be difficult in children.

CONCLUSION

Our case highlights a rare presentation of Ewing sarcoma in the cervical spine, infrequently reported in medical literature. It also demonstrates the success of a novel surgical approach that avoids spinal fixation in children.

摘要

引言与意义

尤因肉瘤是一种罕见的恶性骨肿瘤,可主要累及颈椎。症状可能并不总是出现,但肌肉无力是疾病进展的关键指标,需要紧急手术干预以减轻脊髓压力。

病例介绍

我们报告一例儿童患者,其左上肢突然出现肌肉无力。脊柱磁共振成像显示颈椎有一个肿瘤压迫脊髓。进行了紧急手术干预,成功切除了大部分肿瘤。随后进行了辅助化疗。

临床讨论

由于其位置,位于颈椎的肿瘤治疗具有挑战性。当出现肌肉无力时,紧急手术可能至关重要。本病例展示了一种通过椎骨棘突的新型手术方法,避免了椎板切除术和脊柱固定的需要,而这在儿童中可能较为困难。

结论

我们的病例突出了尤因肉瘤在颈椎的罕见表现,医学文献中鲜有报道。它还展示了一种避免儿童脊柱固定的新型手术方法的成功。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea59/11318468/628bf42e3f3b/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea59/11318468/d77a44dc159c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea59/11318468/d35d647d7312/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea59/11318468/628bf42e3f3b/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea59/11318468/d77a44dc159c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea59/11318468/d35d647d7312/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea59/11318468/628bf42e3f3b/gr3.jpg

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