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想学习?再想想!

Want to learn? think again!

机构信息

Neuroscience Institute, New York University, New York, NY, USA.

出版信息

Sci Prog. 2024 Jul-Sep;107(3):368504241266577. doi: 10.1177/00368504241266577.

DOI:10.1177/00368504241266577
PMID:39043383
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11271117/
Abstract

One of the best ways to improve new learning and increase memory strength is by reprocessing the recently acquired information, for example, by thinking of it again. Synaptic plasticity, the process by which neurons change the strength of their connections with each other, is fundamental for learning and memory formation. Yet, at present, it is unclear how reprocessing information drives synaptic plasticity to support memory improvement. A new study suggests that reprocessing enhances memory formation by recruiting more synapses to represent the new memory, thus increasing its strength.

摘要

提高新学习和增强记忆强度的最佳方法之一是对最近获得的信息进行再处理,例如再次思考它。突触可塑性是神经元改变彼此之间连接强度的过程,是学习和记忆形成的基础。然而,目前尚不清楚信息再处理如何驱动突触可塑性来支持记忆改善。一项新的研究表明,通过招募更多的突触来表示新记忆,再处理增强了记忆形成,从而增加了记忆的强度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2abc/11271117/4c691dfa33af/10.1177_00368504241266577-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2abc/11271117/e3a3f2a0a74a/10.1177_00368504241266577-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2abc/11271117/968c7c9b4a6f/10.1177_00368504241266577-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2abc/11271117/4c691dfa33af/10.1177_00368504241266577-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2abc/11271117/e3a3f2a0a74a/10.1177_00368504241266577-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2abc/11271117/968c7c9b4a6f/10.1177_00368504241266577-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2abc/11271117/4c691dfa33af/10.1177_00368504241266577-fig3.jpg

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本文引用的文献

1
Anti-Hebbian plasticity in the motor cortex promotes defensive freezing.运动皮层中的拮抗Hebbian 可塑性促进防御性冻结。
Curr Biol. 2023 Aug 21;33(16):3465-3477.e5. doi: 10.1016/j.cub.2023.07.021. Epub 2023 Aug 4.
2
Engram neurons: Encoding, consolidation, retrieval, and forgetting of memory.记忆印痕神经元:记忆的编码、巩固、提取和遗忘。
Mol Psychiatry. 2023 Aug;28(8):3207-3219. doi: 10.1038/s41380-023-02137-5. Epub 2023 Jun 28.
3
Freezing revisited: coordinated autonomic and central optimization of threat coping.重温冻结:协调自主和中枢优化威胁应对。
Nat Rev Neurosci. 2022 Sep;23(9):568-580. doi: 10.1038/s41583-022-00608-2. Epub 2022 Jun 27.
4
Conditional and unconditional components of aversively motivated freezing, flight and darting in mice.条件性和非条件性回避性动机导致的冻结、逃避和猛冲行为的成分在小鼠中的表现。
Elife. 2022 May 26;11:e75663. doi: 10.7554/eLife.75663.
5
Prefrontal inhibition drives formation and dynamic expression of probabilistic Pavlovian fear conditioning.前额叶抑制驱动概率性条件恐惧形成和动态表达。
Cell Rep. 2021 Aug 10;36(6):109503. doi: 10.1016/j.celrep.2021.109503.
6
Neocortical Layer 1: An Elegant Solution to Top-Down and Bottom-Up Integration.新皮质层 1:上下贯通整合的优雅解决方案。
Annu Rev Neurosci. 2021 Jul 8;44:221-252. doi: 10.1146/annurev-neuro-100520-012117. Epub 2021 Mar 17.
7
Nonmonotonic Plasticity: How Memory Retrieval Drives Learning.非单调塑性:记忆提取如何驱动学习。
Trends Cogn Sci. 2019 Sep;23(9):726-742. doi: 10.1016/j.tics.2019.06.007. Epub 2019 Jul 26.
8
Fear conditioning and extinction induce opposing changes in dendritic spine remodeling and somatic activity of layer 5 pyramidal neurons in the mouse motor cortex.恐惧条件反射和消退会引起小鼠运动皮层第 5 层锥体神经元树突棘重塑和体细胞活动的相反变化。
Sci Rep. 2019 Mar 15;9(1):4619. doi: 10.1038/s41598-019-40549-y.
9
Perspectives on classical controversies about the motor cortex.关于运动皮层经典争议的观点
J Neurophysiol. 2017 Sep 1;118(3):1828-1848. doi: 10.1152/jn.00795.2016. Epub 2017 Jun 14.
10
Neural plasticity and behavior - sixty years of conceptual advances.神经可塑性与行为——六十年的概念进展
J Neurochem. 2016 Oct;139 Suppl 2:179-199. doi: 10.1111/jnc.13580. Epub 2016 Mar 10.