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抗菌药物耐药性:无声的大流行。

Antimicrobial resistance: a silent pandemic.

出版信息

Nat Commun. 2024 Jul 23;15(1):6198. doi: 10.1038/s41467-024-50457-z.

Abstract

Antimicrobial resistance (AMR) occurs when microorganisms (bacteria, viruses, fungi and parasites) no longer respond to antimicrobials, rendering these specific treatments ineffective. Subsequently, this narrows the options for clinical treatment and increases the risk of complications, hospital admissions, and mortality rates. Ultimately, infections become more difficult to treat. The concern of AMR is not new, yet the COVID-19 pandemic has further highlighted this global burden and raised questions regarding the preparedness for the fight against increasing cases of AMR. In a joint collaboration, , and have launched a Collection and call for papers, inviting submissions of papers that advance our understanding of all aspects of AMR, as outlined in the Collection scope.

摘要

当微生物(细菌、病毒、真菌和寄生虫)对抗菌药物不再敏感,使这些特定的治疗方法无效时,就会发生抗菌药物耐药性(AMR)。随后,这就缩小了临床治疗的选择范围,并增加了并发症、住院和死亡率的风险。最终,感染变得更难治疗。对抗菌药物耐药性的关注并不是什么新鲜事,但 COVID-19 大流行进一步凸显了这一全球性负担,并引发了人们对对抗不断增加的抗菌药物耐药性病例的准备情况的质疑。在一次合作中, 和 发布了一个特刊和论文征集,邀请提交论文,以推进我们对抗菌药物耐药性各个方面的理解,如特刊范围所述。

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