Zewudie Bitew Tefera, Geze Tenaw Shegaw, Solomon Mamo, Mesfin Yibeltal, Abebe Haimanot, Mekonnen Zebene, Tesfa Shegaw, Chekole Temere Bogale, Aynalem Mewahegn Agerie, Lankrew Tadele, Sewale Yihenew
Department of Nursing, College of Medicine and Health Science, Wolkite University, Wolkite, Ethiopia.
Department of Midwifery, College of Medicine and Health Science, Wolkite University, Wolkite, Ethiopia.
SAGE Open Med. 2022 Apr 29;10:20503121221094454. doi: 10.1177/20503121221094454. eCollection 2022.
The study aimed to assess the magnitude of undiagnosed hypertension, and its associated factors among adult HIV-positive patients receiving antiretroviral therapy at Butajira General Hospital, southern Ethiopia.
We applied an institutional-based cross-sectional study design at Butajira General Hospital from 1 May to 1 July 2021. We used a systematic random sampling technique to select the total number of participants. A structured interviewer-administered questionnaire was applied to collect the data (sociodemographic characteristics, clinical-related factors, and lifestyle-related factors from the study participants. Data were entered using Epi-data version 3.1 and analyzed by statistical package for social science version 25. We applied a multivariable logistic regression analysis model to identify variables significantly associated with hypertension.
The study comprised 388 participants with 39 years (10.6 SD) as the mean age of the participants. Of the total participants, 235 (60.6%) were female. In this study the magnitude of undiagnosed hypertension among HIV-positive patients was 18.8% (95% CI: 14.7%-23.2%). Having comorbidity of diabetes mellitus (adjusted odds ratio = 5.29, 95% CI: 2.154, 12.99), habit of alcohol drinking (adjusted odds ratio = 2.909, 95% CI: 1.306, 6.481), duration of antiretroviral therapy ⩾ 5 years (adjusted odds ratio = 3.087, 95% CI: 1.558, 6.115), and age ⩾ 40 years (adjusted odds ratio = 2.642, 95% CI: 1.450, 4.813) were factors significantly associated with undiagnosed hypertension.
The magnitude of undiagnosed hypertension among HIV-positive patients attending the antiretroviral therapy clinic of Butajira General Hospital is high. The findings of this study implied that HIV-positive patients attending antiretroviral therapy clinics should be monitored routinely for hypertension; especially participants aged ⩾40 years, highly active antiretroviral therapy duration ⩾5 years, having diabetes mellitus comorbidity need more attention. Primary healthcare integration is also vital to enhance the health of HIV-positive patients on antiretroviral therapy.
本研究旨在评估埃塞俄比亚南部布塔吉拉综合医院接受抗逆转录病毒治疗的成年HIV阳性患者中未诊断高血压的严重程度及其相关因素。
2021年5月1日至7月1日,我们在布塔吉拉综合医院采用基于机构的横断面研究设计。我们使用系统随机抽样技术选择参与者总数。应用结构化访谈问卷收集数据(研究参与者的社会人口学特征、临床相关因素和生活方式相关因素)。数据使用Epi-data 3.1版本录入,并通过社会科学统计软件包25版进行分析。我们应用多变量逻辑回归分析模型来识别与高血压显著相关的变量。
该研究包括388名参与者,参与者的平均年龄为39岁(标准差10.6)。在所有参与者中,235名(60.6%)为女性。在本研究中,HIV阳性患者中未诊断高血压的严重程度为18.8%(95%置信区间:14.7%-23.2%)。患有糖尿病合并症(调整后的优势比=5.29,95%置信区间:2.154,12.99)、饮酒习惯(调整后的优势比=2.909,95%置信区间:1.306,6.481)、抗逆转录病毒治疗持续时间⩾5年(调整后的优势比=3.087,95%置信区间:1.558,6.115)以及年龄⩾40岁(调整后的优势比=2.642,95%置信区间:1.450,4.813)是与未诊断高血压显著相关的因素。
在布塔吉拉综合医院抗逆转录病毒治疗门诊就诊的HIV阳性患者中,未诊断高血压的严重程度较高。本研究结果表明,在抗逆转录病毒治疗门诊就诊的HIV阳性患者应定期监测高血压;特别是年龄⩾40岁、高效抗逆转录病毒治疗持续时间⩾5年、患有糖尿病合并症的参与者需要更多关注。基层医疗整合对于提高接受抗逆转录病毒治疗的HIV阳性患者的健康水平也至关重要。