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A multi-cancer early detection (MCED) test: clinical update for GPs.

作者信息

Save Tanvi, Neal Richard D, Round Thomas

机构信息

School of Life Course & Population Sciences, King's College London, London.

APEx (Exeter Collaboration for Academic Primary Care), Faculty of Health & Life Sciences, University of Exeter, Exeter.

出版信息

Br J Gen Pract. 2024 Jul 25;74(745):380-382. doi: 10.3399/bjgp24X739113. Print 2024 Aug.

DOI:10.3399/bjgp24X739113
PMID:39054076
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11299699/
Abstract
摘要

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本文引用的文献

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2
Multi-Cancer Early Detection: The New Frontier in Cancer Early Detection.多癌种早期检测：癌症早期检测的新前沿。
Annu Rev Med. 2024 Jan 29;75:67-81. doi: 10.1146/annurev-med-050522-033624. Epub 2023 Sep 20.
3
Multi-cancer early detection test in symptomatic patients referred for cancer investigation in England and Wales (SYMPLIFY): a large-scale, observational cohort study.英国和威尔士因癌症检查而转诊的有症状患者的多癌早期检测试验（SYMPLIFY）：一项大规模观察性队列研究
Lancet Oncol. 2023 Jul;24(7):733-743. doi: 10.1016/S1470-2045(23)00277-2. Epub 2023 Jun 20.
4
Cell-Free DNA-Based Multi-Cancer Early Detection Test in an Asymptomatic Screening Population (NHS-Galleri): Design of a Pragmatic, Prospective Randomised Controlled Trial.基于游离DNA的无症状筛查人群多癌早期检测试验（NHS-Galleri）：一项实用、前瞻性随机对照试验的设计
Cancers (Basel). 2022 Oct 1;14(19):4818. doi: 10.3390/cancers14194818.
5
The PATHFINDER Study: Assessment of the Implementation of an Investigational Multi-Cancer Early Detection Test into Clinical Practice.探索者研究：评估一种研究性多癌早期检测测试在临床实践中的实施情况。
Cancers (Basel). 2021 Jul 13;13(14):3501. doi: 10.3390/cancers13143501.
6
Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set.使用独立验证集对靶向甲基化的多癌种早期检测测试进行临床验证。
Ann Oncol. 2021 Sep;32(9):1167-1177. doi: 10.1016/j.annonc.2021.05.806. Epub 2021 Jun 24.
7
Prognostic Significance of Blood-Based Multi-cancer Detection in Plasma Cell-Free DNA.基于游离血浆 DNA 的多癌种血液检测的预后意义。
Clin Cancer Res. 2021 Aug 1;27(15):4221-4229. doi: 10.1158/1078-0432.CCR-21-0417. Epub 2021 Jun 4.
8
Circulating tumor DNA (ctDNA) as a pan-cancer screening test: is it finally on the horizon?循环肿瘤 DNA（ctDNA）作为一种泛癌种筛查检测手段：它是否终于要面世了？
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