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2
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Replication and segregation of plasmids containing cis-acting regulatory sites of silent mating-type genes in Saccharomyces cerevisiae are controlled by the SIR genes.酿酒酵母中含有沉默交配型基因顺式作用调控位点的质粒的复制和分离受SIR基因控制。
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7
Cloning and characterization of four SIR genes of Saccharomyces cerevisiae.酿酒酵母四个SIR基因的克隆与特性分析
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8
Genetic and molecular characterization of suppressors of SIR4 mutations in Saccharomyces cerevisiae.酿酒酵母中SIR4突变抑制子的遗传与分子特征分析
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本文引用的文献

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The Relations of Inversions in the X Chromosome of Drosophila Melanogaster to Crossing over and Disjunction.果蝇X染色体倒位与交换及分离的关系
Genetics. 1936 Sep;21(5):554-604. doi: 10.1093/genetics/21.5.554.
2
A new mapping method employing a meiotic rec-mutant of yeast.一种采用酵母减数分裂rec突变体的新映射方法。
Genetics. 1982 Mar;100(3):387-412. doi: 10.1093/genetics/100.3.387.
3
The genetic control of sporulation in Saccharomyces. II. Dominance and complementation of mutants of meiosis and spore formation.酿酒酵母中孢子形成的遗传控制。II. 减数分裂和孢子形成突变体的显性和互补作用。
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Detection of specific sequences among DNA fragments separated by gel electrophoresis.在通过凝胶电泳分离的DNA片段中检测特定序列。
J Mol Biol. 1975 Nov 5;98(3):503-17. doi: 10.1016/s0022-2836(75)80083-0.
5
A suppressor of mating-type locus mutations in Saccharomyces cerevisiae: evidence for and identification of cryptic mating-type loci.酿酒酵母交配型基因座突变的抑制因子：隐蔽交配型基因座的证据及鉴定
Genetics. 1979 Dec;93(4):877-901. doi: 10.1093/genetics/93.4.877.
6
High-frequency transformation of yeast: autonomous replication of hybrid DNA molecules.酵母的高频转化：杂种DNA分子的自主复制
Proc Natl Acad Sci U S A. 1979 Mar;76(3):1035-9. doi: 10.1073/pnas.76.3.1035.
7
Transformation of yeast by a replicating hybrid plasmid.通过复制型杂种质粒对酵母进行转化。
Nature. 1978 Sep 14;275(5676):104-9. doi: 10.1038/275104a0.
8
Unique arrangement of coding sequences for 5 S, 5.8 S, 18 S and 25 S ribosomal RNA in Saccharomyces cerevisiae as determined by R-loop and hybridization analysis.
J Mol Biol. 1978 Aug 15;123(3):387-404. doi: 10.1016/0022-2836(78)90086-4.

酵母基因SIR1、SIR3和SIR4的图谱位置。

Map positions of yeast genes SIR1, SIR3 and SIR4.

作者信息

Ivy J M, Hicks J B, Klar A J

出版信息

Genetics. 1985 Dec;111(4):735-44. doi: 10.1093/genetics/111.4.735.

DOI:10.1093/genetics/111.4.735
PMID:3905505
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1202668/
Abstract

The HML and HMR loci in the yeast Saccharomyces cerevisiae each contain a complete copy of mating-type information. HML and HMR normally are transcriptionally inactive due to four unlinked genes, known as MAR or SIR or CMT. The map position of MAR1 (SIR2) has been reported previously; it is located on the left arm of chromosome IV, 27 cM from the centromere. Using conventional meiotic and mitotic mapping combined with recombinant DNA techniques, we have mapped three other SIR genes. SIR1 maps near the telomere of the right arm of chromosome XI; SIR3 (MAR2) maps to the right arm of chromosome XII, 31 cM distal to URA4; and SIR4 maps to the right arm of chromosome IV, 16 cM proximal to LYS4.

摘要

酵母酿酒酵母中的HML和HMR基因座各自包含一份完整的交配型信息拷贝。由于四个不连锁的基因，即MAR或SIR或CMT，HML和HMR通常处于转录无活性状态。MAR1（SIR2）的图谱位置先前已有报道；它位于第四条染色体的左臂，距着丝粒27厘摩。利用传统的减数分裂和有丝分裂图谱分析结合重组DNA技术，我们已对其他三个SIR基因进行了定位。SIR1定位于第十一条染色体右臂的端粒附近；SIR3（MAR2）定位于第十二条染色体的右臂，距URA4远端31厘摩；SIR4定位于第四条染色体的右臂，距LYS4近端16厘摩。