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巴基斯坦开伯尔-普赫图赫瓦省肾结石的危险因素:一项描述性横断面研究。

Risk Factors of Kidney Stones in Khyber Pakhtunkhwa, Pakistan: A Descriptive Cross-Sectional Study.

作者信息

Waqas Muhammad, Khan Zaryaab A, Ahmad Shabeer, Akbar Siddiq, Khalid Nayab

机构信息

Urology, Hayatabad Medical Complex, Peshawar, PAK.

Nephrology, Khyber Teaching Hospital, Peshawar, PAK.

出版信息

Cureus. 2024 Jun 24;16(6):e63080. doi: 10.7759/cureus.63080. eCollection 2024 Jun.

Abstract

Introduction Renal calculi, commonly known as kidney stones, affect approximately 12% of the global population, often resulting in mild to severe pain and complications such as infection and renal failure. The causes are multifactorial, involving lifestyle factors, genetic predisposition, and various medical conditions. Despite advancements in treatment, the incidence of kidney stones is on the rise, especially in regions like Asia's stone belt, which includes Pakistan as well. This study investigates the risk factors associated with kidney stones in patients at the Hayatabad Medical Complex, Peshawar, Pakistan, with the goal of informing healthcare policymakers and educating patients to reduce the prevalence and economic burden of the disease in the region. Methods Over a four-month period, 173 patients admitted to the department with confirmed urolithiasis were recruited using a consensus sampling technique. Inclusion criteria were adults aged 18 or older residing in Khyber Pakhtunkhwa, Pakistan. Exclusion criteria included pregnancy, incomplete medical records, secondary causes of renal stones, and unwillingness to participate. Data on socio-demographic factors, clinical history, and lifestyle habits were collected through structured interviews. Descriptive analysis was performed using SPSS software version 23 (IBM Inc, Armonk, New York). Results The study findings indicate that kidney stones were notably prevalent among patients aged 31 to 45 years, with 85 cases identified, comprising 49.1% of the study participants. Furthermore, a significant proportion of affected individuals were males, accounting for 94 cases (54.3%). Those with primary schooling or lower education comprised 106 cases (61.3%), and 124 individuals (71.7%) had lower socioeconomic status. Overweight individuals constituted 81 cases (45.8%) of the total. The study also found a considerable prevalence among residents of rural areas, with 128 cases identified (74.0%). Additionally, 104 cases (60.1%) had a personal history of renal stones. Insufficient water intake was prevalent among 122 individuals (70.5%), while daily consumers of more than one cup of tea also exhibited a higher prevalence, with 97 cases identified (56.1%). Lastly, individuals with a high sodium diet were notably affected, with 112 cases (64.7%) recorded. Conclusion In summary, individuals aged 31-45, males, those residing in rural areas, with lower educational and socioeconomic status, insufficient water intake, a diet high in sodium, personal history of kidney stones, and overweight are at higher risk of urolithiasis. Public education on preventive measures is essential to decrease the incidence of kidney stones and enhance quality of life.

摘要

引言

肾结石,通常被称为肾结石,影响着全球约12%的人口,常常导致轻至重度疼痛以及感染和肾衰竭等并发症。其病因是多因素的,涉及生活方式因素、遗传易感性和各种医疗状况。尽管治疗方面有所进步,但肾结石的发病率仍在上升,尤其是在亚洲结石带等地区,巴基斯坦也包括在内。本研究调查了巴基斯坦白沙瓦哈亚塔巴德医疗中心患者中与肾结石相关的危险因素,目的是为医疗保健政策制定者提供信息,并教育患者以降低该地区疾病的患病率和经济负担。

方法

在四个月的时间里,采用共识抽样技术招募了173名确诊为尿路结石的该科室住院患者。纳入标准为居住在巴基斯坦开伯尔-普赫图赫瓦省的18岁及以上成年人。排除标准包括怀孕、医疗记录不完整、肾结石的继发性病因以及不愿参与。通过结构化访谈收集了社会人口统计学因素、临床病史和生活习惯的数据。使用SPSS软件版本23(IBM公司,纽约州阿蒙克)进行描述性分析。

结果

研究结果表明,肾结石在31至45岁的患者中尤为普遍,共识别出85例,占研究参与者的49.1%。此外,受影响个体中很大一部分是男性,占94例(54.3%)。小学及以下学历者有106例(61.3%),社会经济地位较低的有124人(71.7%)。超重个体占总数的81例(45.8%)。研究还发现农村地区居民的患病率相当高,共识别出128例(74.0%)。此外,104例(60.1%)有肾结石个人史。122人(70.5%)存在饮水不足的情况,而每天饮用超过一杯茶的消费者患病率也较高,共识别出97例(56.1%)。最后,高钠饮食的个体受影响尤为明显,记录在案的有112例(64.7%)。

结论

总之,31 - 45岁的个体、男性、居住在农村地区的人、教育和社会经济地位较低的人、饮水不足、高钠饮食、有肾结石个人史以及超重的人患尿路结石的风险更高。开展关于预防措施的公众教育对于降低肾结石发病率和提高生活质量至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/070c/11269969/84b8a0e8c307/cureus-0016-00000063080-i01.jpg

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