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硅actin与海绵生物二氧化硅的结构多样性。

Silactins and Structural Diversity of Biosilica in Sponges.

作者信息

Ehrlich Hermann, Voronkina Alona, Tabachniсk Konstantin, Kubiak Anita, Ereskovsky Alexander, Jesionowski Teofil

机构信息

Center of Advanced Technology, Adam Mickiewicz University, Uniwersytetu Poznańskiego 10, 61-614 Poznan, Poland.

Faculty of Chemical Technology, Institute of Chemical Technology and Engineering, Poznan University of Technology, Berdychowo 4, 60-965 Poznan, Poland.

出版信息

Biomimetics (Basel). 2024 Jun 27;9(7):393. doi: 10.3390/biomimetics9070393.

DOI:10.3390/biomimetics9070393
PMID:39056834
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11274843/
Abstract

Sponges (phylum Porifera) were among the first metazoans on Earth, and represent a unique global source of highly structured and diverse biosilica that has been formed and tested over more than 800 million years of evolution. Poriferans are recognized as a unique archive of siliceous multiscaled skeletal constructs with superficial micro-ornamentation patterned by biopolymers. In the present study, spicules and skeletal frameworks of selected representatives of sponges in such classes as Demospongiae, Homoscleromorpha, and Hexactinellida were desilicified using 10% HF with the aim of isolating axial filaments, which resemble the shape and size of the original structures. These filaments were unambiguously identified in all specimens under study as F-actin, using the highly specific indicators iFluor™ 594-Phalloidin, iFluor™ 488-Phalloidin, and iFluor™ 350-Phalloidin. The identification of this kind of F-actins, termed for the first time as silactins, as specific pattern drivers in skeletal constructs of sponges opens the way to the fundamental understanding of their skeletogenesis. Examples illustrating the biomimetic potential of sophisticated poriferan biosilica patterned by silactins are presented and discussed.

摘要

海绵动物（多孔动物门）是地球上最早出现的后生动物之一，代表了一种独特的全球高结构化和多样化生物二氧化硅来源，这种生物二氧化硅在超过8亿年的进化过程中形成并经过了检验。海绵动物被认为是硅质多尺度骨骼结构的独特档案库，其表面微观装饰由生物聚合物构成图案。在本研究中，使用10%的氢氟酸对寻常海绵纲、同骨海绵纲和六放海绵纲等海绵类群的选定代表的骨针和骨骼框架进行脱硅处理，目的是分离出形状和大小与原始结构相似的轴向细丝。使用高度特异性指示剂iFluor™ 594-鬼笔环肽、iFluor™ 488-鬼笔环肽和iFluor™ 350-鬼笔环肽，在所有研究标本中明确鉴定出这些细丝为F-肌动蛋白。这种首次被称为硅肌动蛋白的F-肌动蛋白作为海绵动物骨骼结构中的特定图案驱动因子的鉴定，为从根本上理解其骨骼生成开辟了道路。文中展示并讨论了一些示例，这些示例说明了由硅肌动蛋白构成图案的复杂海绵动物生物二氧化硅的仿生潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f22/11274843/eabb362d9d02/biomimetics-09-00393-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f22/11274843/3eee6c1c6911/biomimetics-09-00393-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f22/11274843/ab06cbe299d5/biomimetics-09-00393-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f22/11274843/37cf35d9224c/biomimetics-09-00393-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f22/11274843/574fa37e4793/biomimetics-09-00393-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f22/11274843/f93e16cb5dd9/biomimetics-09-00393-g005a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f22/11274843/ce308ff42b1f/biomimetics-09-00393-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f22/11274843/42b709707e4b/biomimetics-09-00393-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f22/11274843/15fda925b2a8/biomimetics-09-00393-g008a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f22/11274843/2eae6150cef2/biomimetics-09-00393-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f22/11274843/d6e9906f3084/biomimetics-09-00393-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f22/11274843/37dc8e2e4046/biomimetics-09-00393-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f22/11274843/eabb362d9d02/biomimetics-09-00393-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f22/11274843/3eee6c1c6911/biomimetics-09-00393-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f22/11274843/ab06cbe299d5/biomimetics-09-00393-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f22/11274843/37cf35d9224c/biomimetics-09-00393-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f22/11274843/574fa37e4793/biomimetics-09-00393-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f22/11274843/f93e16cb5dd9/biomimetics-09-00393-g005a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f22/11274843/ce308ff42b1f/biomimetics-09-00393-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f22/11274843/42b709707e4b/biomimetics-09-00393-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f22/11274843/15fda925b2a8/biomimetics-09-00393-g008a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f22/11274843/2eae6150cef2/biomimetics-09-00393-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f22/11274843/d6e9906f3084/biomimetics-09-00393-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f22/11274843/37dc8e2e4046/biomimetics-09-00393-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f22/11274843/eabb362d9d02/biomimetics-09-00393-g012.jpg

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