Listorti Valeria, Guardone Lisa, Piccinini Carolina, Martini Isabella, Ferraris Carla, Ligotti Carmela, Cristina Maria Luisa, Pussini Nicola, Pitti Monica, Razzuoli Elisabetta
Istituto Zooprofilattico Sperimentale of Piemonte, Liguria and Valle d'Aosta, Via Bologna 148, 10154 Turin, Italy.
Department of Veterinary Sciences, University of Pisa, Viale Delle Piagge 2, 56124 Pisa, Italy.
Pathogens. 2024 Jul 11;13(7):576. doi: 10.3390/pathogens13070576.
Wildlife may represent an important source of infectious diseases for humans and other wild and domestic animals. Wild ruminants can harbour and transmit Shiga toxin-producing (STEC) to humans, and some strains even carry important antimicrobial resistance. In this study, 289 livers of wild roe deer, fallow deer, red deer and chamois collected in Liguria, north-west Italy, from 2019 to 2023 were analysed. Overall, 44 STEC strains were isolated from 28 samples. The characterisation of serogroups showed the presence of O104, O113, O145 and O146 serogroups, although for 28 colonies, the serogroup could not be determined. The most prevalent Shiga toxin gene in isolated strains was , and more specifically the subtype . The other retrieved subtypes were and . The isolated strains generally proved to be susceptible to the tested antimicrobials. However, multi-drug resistances against highly critical antimicrobials were found in one strain isolated from a roe deer. This study highlights the importance of wildlife monitoring in the context of a "One Health" approach.
野生动物可能是人类以及其他野生动物和家畜传染病的重要来源。野生反刍动物可携带产志贺毒素大肠杆菌（STEC）并将其传播给人类，一些菌株甚至具有重要的抗菌耐药性。在本研究中，对2019年至2023年期间在意大利西北部利古里亚采集的289份狍、黇鹿、马鹿和岩羚羊的肝脏进行了分析。总体而言，从28个样本中分离出44株STEC菌株。血清群鉴定显示存在O104、O113、O145和O146血清群，不过有28个菌落无法确定血清群。分离菌株中最常见的志贺毒素基因是 ，更具体地说是 亚型。其他检测到的亚型是 和 。分离菌株总体上对所测试的抗菌药物敏感。然而，在一株从狍分离出的菌株中发现了对高度关键抗菌药物的多重耐药性。本研究强调了在“同一健康”方法背景下进行野生动物监测的重要性。
