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生物活性玻璃作为可注射材料的现状与未来展望

Current and Future Perspectives of Bioactive Glasses as Injectable Material.

作者信息

Mîrț Andreea-Luiza, Ficai Denisa, Oprea Ovidiu-Cristian, Vasilievici Gabriel, Ficai Anton

机构信息

Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Chemical Engineering and Biotechnologies, National University of Science and Technology Politehnica Bucharest, Gh. Polizu 1-7, 011061 Bucharest, Romania.

National Center for Scientific Research for Food Safety, National University of Science and Technology Politehnica Bucharest, Splaiul Independentei 313, 060042 Bucharest, Romania.

出版信息

Nanomaterials (Basel). 2024 Jul 13;14(14):1196. doi: 10.3390/nano14141196.

Abstract

This review covers recent compositions of bioactive glass, with a specific emphasis on both inorganic and organic materials commonly utilized as matrices for injectable materials. The major objective is to highlight the predominant bioactive glass formulations and their clinical applications in the biomedical field. Previous studies have highlighted the growing interest among researchers in bioactive glasses, acknowledging their potential to yield promising outcomes in this field. As a result of this increased interest, investigations into bioactive glass have prompted the creation of composite materials and, notably, the development of injectable composites as a minimally invasive method for administering the material within the human body. Injectable materials have emerged as a promising avenue to mitigate various challenges. They offer several advantages, including minimizing invasive surgical procedures, reducing patient discomfort, lowering the risk of postoperative infection and decreasing treatment expenses. Additionally, injectable materials facilitate uniform distribution, allowing for the filling of defects of any shape.

摘要

本综述涵盖了生物活性玻璃的最新成分,特别强调了通常用作可注射材料基质的无机和有机材料。主要目的是突出主要的生物活性玻璃配方及其在生物医学领域的临床应用。先前的研究强调了研究人员对生物活性玻璃的兴趣日益浓厚,认可其在该领域产生有前景结果的潜力。由于这种兴趣的增加,对生物活性玻璃的研究促使了复合材料的产生,特别是可注射复合材料的发展,作为一种在人体内给药的微创方法。可注射材料已成为减轻各种挑战的有前景途径。它们具有几个优点,包括最大限度地减少侵入性外科手术、减轻患者不适、降低术后感染风险和减少治疗费用。此外,可注射材料便于均匀分布,能够填充任何形状的缺损。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4027/11280465/269c76ca6aac/nanomaterials-14-01196-g001.jpg

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