Department of Neuroscience, Yale University, New Haven, CT 06510, USA; Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06510, USA.
Department of Neuroscience, Yale University, New Haven, CT 06510, USA; Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06510, USA.
Cell Rep. 2024 Aug 27;43(8):114557. doi: 10.1016/j.celrep.2024.114557. Epub 2024 Jul 25.
Predictive remapping of receptive fields (RFs) is thought to be one of the critical mechanisms for enforcing perceptual stability during eye movements. While RF remapping has been observed in several cortical areas, its role in early visual cortex and its consequences on the tuning properties of neurons have been poorly understood. Here, we track remapping RFs in hundreds of neurons from visual area V2 while subjects perform a cued saccade task. We find that remapping is widespread in area V2 across neurons from all recorded cortical layers and cell types. Furthermore, our results suggest that remapping RFs not only maintain but also transiently enhance their feature selectivity due to untuned suppression. Taken together, these findings shed light on the dynamics and prevalence of remapping in the early visual cortex, forcing us to revise current models of perceptual stability during saccadic eye movements.
预测性感受野（RF）重映射被认为是在眼球运动期间强制实现知觉稳定的关键机制之一。虽然在几个皮质区域中观察到了 RF 重映射，但它在早期视觉皮层中的作用及其对神经元调谐特性的影响还知之甚少。在这里，我们在受试者执行提示性扫视任务时，从视觉区域 V2 中跟踪数百个神经元的 RF 重映射。我们发现，重映射在来自所有记录的皮质层和细胞类型的区域 V2 中广泛存在于神经元中。此外，我们的结果表明，由于未调谐的抑制，重映射的 RF 不仅保持而且暂时增强了它们的特征选择性。总的来说，这些发现揭示了早期视觉皮层中重映射的动态和普遍性，迫使我们修正在扫视眼球运动期间的知觉稳定性的当前模型。
