Massachusetts General Hospital and Harvard Medical School, Boston, US; Mass General Brigham Data Science Office, Boston, US.
International Atomic Energy Agency, Vienna, Austria.
Phys Med. 2024 Aug;124:103431. doi: 10.1016/j.ejmp.2024.103431. Epub 2024 Jul 25.
The objective of our IAEA-coordinated international study was to assess CT practices and radiation doses from multiple hospitals across several African countries.
The study included 13 hospitals from Africa which contributed information on minimum of 20 consecutive patients who underwent head, chest, and/or abdomen-pelvis CT. Prior to the data recording step, all hospitals had a mandatory one-hour training on the best practices in recording the relevant data elements. The recorded data elements included patient age, weight, protocol name, scanner information, acquisition parameters, and radiation dose descriptors including phase-specific CT dose index volume (CTDI in mGy) and dose length product (DLP in mGy.cm). We estimated the median and interquartile range of body-region specific CTDI and DLP and compared data across sites and countries using the Kruskal-Wallis H Test for non-normal distribution, analysis of variance.
A total of 1061 patients (mean age 50 ± 19 years) were included in the study. 16 % of CT exams had no stated clinical indications for CT examinations of the head (32/343, 9 %), chest (50/281, 18 %), abdomen-pelvis (67/243, 28 %), and/or chest-abdomen-pelvis CT (24/194, 12 %). Most hospitals used multiphase CT protocols for abdomen-pelvis (9/11 hospitals) and chest CT (10/12 hospitals), regardless of clinical indications. Total median DLP values for head (953 mGy.cm), chest (405 mGy.cm), and abdomen-pelvis (1195 mGy.cm) CT were above the UK, German, and American College of Radiology Diagnostic Reference Levels (DRLs).
Concerning variations in CT practices and protocols across several hospitals in Africa were demonstrated, emphasizing the need for better protocol optimization to improve patient safety.
我们的国际研究由国际原子能机构协调,旨在评估多个非洲国家多家医院的 CT 实践和辐射剂量。
该研究包括来自非洲的 13 家医院,这些医院提供了至少 20 名连续接受头部、胸部和/或腹部-骨盆 CT 检查的患者的信息。在记录数据之前,所有医院都必须进行一个小时的关于记录相关数据元素的最佳实践的培训。记录的数据元素包括患者年龄、体重、方案名称、扫描仪信息、采集参数以及辐射剂量描述符,包括特定相位的 CT 剂量指数容积(mGy 中的 CTDI)和剂量长度乘积(mGy·cm 中的 DLP)。我们估计了身体部位特定 CTDI 和 DLP 的中位数和四分位数范围,并使用非正态分布的 Kruskal-Wallis H 检验和方差分析比较了不同地点和国家的数据。
共有 1061 名患者(平均年龄 50 ± 19 岁)纳入研究。16%的 CT 检查没有明确的头部(32/343,9%)、胸部(50/281,18%)、腹部-骨盆(67/243,28%)和/或胸部-腹部-骨盆 CT 检查的临床指征(24/194,12%)。大多数医院使用多期 CT 方案进行腹部-骨盆(9/11 家医院)和胸部 CT(10/12 家医院),无论临床指征如何。头部(953 mGy·cm)、胸部(405 mGy·cm)和腹部-骨盆(1195 mGy·cm)CT 的总中位数 DLP 值均高于英国、德国和美国放射学院的诊断参考水平(DRLs)。
该研究表明,非洲多家医院的 CT 实践和方案存在差异,强调需要更好的方案优化以提高患者安全性。