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禁食术语的国际共识。

International consensus on fasting terminology.

机构信息

Institute of Social Medicine, Epidemiology and Health Economics, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany; Department of Internal Medicine and Nature-Based Therapies, Immanuel Hospital Berlin, 14109 Berlin, Germany; Charité Competence Center for Traditional and Integrative Medicine (CCCTIM), Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.

Institute of Social Medicine, Epidemiology and Health Economics, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.

出版信息

Cell Metab. 2024 Aug 6;36(8):1779-1794.e4. doi: 10.1016/j.cmet.2024.06.013. Epub 2024 Jul 25.


DOI:10.1016/j.cmet.2024.06.013
PMID:39059384
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11504329/
Abstract

Although fasting is increasingly applied for disease prevention and treatment, consensus on terminology is lacking. Using Delphi methodology, an international, multidisciplinary panel of researchers and clinicians standardized definitions of various fasting approaches in humans. Five online surveys and a live online conference were conducted with 38 experts, 25 of whom completed all 5 surveys. Consensus was achieved for the following terms: "fasting" (voluntary abstinence from some or all foods or foods and beverages), "modified fasting" (restriction of energy intake to max. 25% of energy needs), "fluid-only fasting," "alternate-day fasting," "short-term fasting" (lasting 2-3 days), "prolonged fasting" (≥4 consecutive days), and "religious fasting." "Intermittent fasting" (repetitive fasting periods lasting ≤48 h), "time-restricted eating," and "fasting-mimicking diet" were discussed most. This study provides expert recommendations on fasting terminology for future research and clinical applications, facilitating communication and cross-referencing in the field.

摘要

尽管禁食在疾病预防和治疗中的应用日益增多,但在术语方面尚未达成共识。本研究采用德尔菲法,召集国际多学科研究人员和临床医生小组,对人类的各种禁食方法进行标准化定义。通过 5 次在线调查和 1 次在线直播会议,对 38 名专家进行了调查,其中 25 名专家完成了所有 5 次调查。以下术语达成了共识:“禁食”(自愿禁食某些或所有食物或食物和饮料)、“改良禁食”(将能量摄入限制在能量需求的 25%以内)、“仅液体禁食”、“隔日禁食”、“短期禁食”(持续 2-3 天)、“长期禁食”(≥4 天)和“宗教禁食”。“间歇性禁食”(重复禁食时间≤48 小时)、“限时进食”和“禁食模拟饮食”讨论最多。本研究为未来的研究和临床应用提供了禁食术语的专家建议,促进了该领域的交流和相互参照。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b4e/11504329/f422b51ca533/nihms-2019353-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b4e/11504329/7e36ed4e382a/nihms-2019353-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b4e/11504329/2c451a7e356d/nihms-2019353-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b4e/11504329/f422b51ca533/nihms-2019353-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b4e/11504329/7e36ed4e382a/nihms-2019353-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b4e/11504329/2c451a7e356d/nihms-2019353-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b4e/11504329/f422b51ca533/nihms-2019353-f0003.jpg

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引用本文的文献

[1]
Case Report: Sustained weight loss and glycemic control from repeated long-term fasting in type 2 diabetes.

Front Clin Diabetes Healthc. 2025-8-7

[2]
Dietary assessment in intermittent fasting: validation of a short food frequency questionnaire vs. food records in diurnal dry fasting and time-restricted eating.

Front Nutr. 2025-7-28

[3]
Intermittent fasting and a no-sugar diet for Long COVID symptoms: a randomized crossover trial.

Sci Rep. 2025-7-29

[4]
A Comprehensive Perspective on the Biological Effects of Intermittent Fasting and Periodic Short-Term Fasting: A Promising Strategy for Optimizing Metabolic Health.

Nutrients. 2025-6-20

[5]
Long-term fasting-induced parasympathetic and sympathetic autonomic nervous system modulation in a subgroup of the GENESIS study.

Int J Obes (Lond). 2025-7-9

[6]
Effects of fasting on HDL particle function and size distribution.

J Lipid Res. 2025-7-5

[7]
Hypoglycemia compensation mechanisms in dry fasting.

Metabol Open. 2025-4-15

[8]
Intermittent fasting for weight loss in night shift workers: a three-arm, superiority randomised clinical trial.

EBioMedicine. 2025-6-18

[9]
Fasting the mitochondria to prevent neurodegeneration: the role of ceramides.

Front Neurosci. 2025-6-4

[10]
Additional Effect of Exercise to Intermittent Fasting on Body Composition and Cardiometabolic Health in Adults With Overweight/obesity: A Systematic Review and Meta-analysis.

Curr Obes Rep. 2025-6-19

本文引用的文献

[1]
A bibliometric analysis of the Fasting-Mimicking Diet.

Front Nutr. 2024-1-23

[2]
A Bibliometric Analysis of Alternate-Day Fasting from 2000 to 2023.

Nutrients. 2023-8-25

[3]
Intestinal Microbiota Reduction Followed by Fasting Discloses Microbial Triggering of Inflammation in Rheumatoid Arthritis.

J Clin Med. 2023-6-28

[4]
When a calorie is not just a calorie: Diet quality and timing as mediators of metabolism and healthy aging.

Cell Metab. 2023-7-11

[5]
Time-Restricted Eating Without Calorie Counting for Weight Loss in a Racially Diverse Population : A Randomized Controlled Trial.

Ann Intern Med. 2023-7

[6]
Targeting Energy Intake and Circadian Biology to Engage Mechanisms of Aging in Older Adults With Obesity: Calorie Restriction and Time-Restricted Eating.

J Gerontol A Biol Sci Med Sci. 2023-6-16

[7]
Early time-restricted eating affects weight, metabolic health, mood, and sleep in adherent completers: A secondary analysis.

Obesity (Silver Spring). 2023-2

[8]
To eat or not to eat-an exploratory randomized controlled trial on fasting and plant-based diet in rheumatoid arthritis (NutriFast-Study).

Front Nutr. 2022-11-2

[9]
The impact of Ramadan fasting on the metabolic syndrome severity in relation to ethnicity and sex: Results of a systematic review and meta-analysis.

Nutr Metab Cardiovasc Dis. 2022-12

[10]
Fasting intervention and its clinical effects on the human host and microbiome.

J Intern Med. 2023-2

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