探讨斋戒对代谢综合征严重程度影响的种族和性别差异：系统评价和荟萃分析的结果。
The impact of Ramadan fasting on the metabolic syndrome severity in relation to ethnicity and sex: Results of a systematic review and meta-analysis.
机构信息
Ministry of Health, Manama, Bahrain; Department of Psychiatry, College of Medicine and Medical Sciences, Arabian Gulf University, Manama, Bahrain.
High Institute of Sport and Physical Education of Sfax, University of Sfax, Sfax 3000, Tunisia; Research Laboratory: Education, Motricity, Sport and Health, EM2S, LR19JS01, University of Sfax, Sfax 3000, Tunisia.
出版信息
Nutr Metab Cardiovasc Dis. 2022 Dec;32(12):2714-2729. doi: 10.1016/j.numecd.2022.09.001. Epub 2022 Sep 12.
AIMS
The primary goal of this meta-analysis was to examine the changes in various components of metabolic syndrome (MetS) in healthy adults who observed Ramadan fasting (RF) before Ramadan (T1) and at the end of RF (T2). A secondary goal was to assess the impact of RF on MetS severity in various ethnic and sex groups using the MetS z-score.
DATA SYNTHESIS
Using PRISMA2020, seven databases were searched for relevant studies published between January 1950 and March 2022. Data extraction involved high-density lipoprotein cholesterol (HDL), triglycerides (TG), fasting blood glucose (FBG), waist circumference (WC), systolic blood pressure (SBP), and diastolic blood pressure (DBP) for T1 and T2, respectively. The MetS z-score was computed according to international diabetes federation criteria. At T1, the pooled estimates of HDL, TG, FBG, WC, SBP, DBP, and MAP were 1.20 [1.13; 1.27] mmol/L, 1.32 [1.23; 1.42] mmol/L, 4.98 [4.82; 5.15] mmol/L, 87.21 [84.21; 90.21] Cm, 114.22 [101.45; 126.99] mmHg, 76.80 [70.12; 83.47] mmHg, and 89.27 [80.56; 97.98] mmHg, respectively. At T2, the pooled estimates of HDL, TG, FBG, WC, SBP, DBP, and MAP were 1.24 [1.18; 1.31] mmol/L, 1.24 [1.14; 1.34] mmol/L, 4.77 [4.55; 4.99] mmol/L, 85.73 [82.83; 88.64] Cm, 109.48 [97.20; 121.75] mmHg, 74.43 [68.01; 80.85] mmHg, and 86.11 [77.74; 94.48] mmHg, respectively. The MetS z-score showed improvement at T2 for all ethnic groups and both sexes by -0.22 [-0.24; -0.01].
CONCLUSIONS
The current meta-analysis suggests that the RF positively impact the MetS components and the overall MetS z-score.
PROSPERO REGISTRATION NUMBER
ID CRD42022329297 OPEN SCIENCE FRAMEWORK IDENTIFIER: DOI 10.17605/OSF.IO/U9H7T.
目的
本荟萃分析的主要目的是研究在斋月前（T1）和斋月结束时（T2）进行斋月禁食（RF）的健康成年人中，代谢综合征（MetS）的各种成分的变化。次要目的是使用 MetS z 分数评估 RF 对不同种族和性别人群 MetS 严重程度的影响。
数据综合
使用 PRISMA2020，在 1950 年 1 月至 2022 年 3 月期间，对 7 个数据库进行了相关研究的检索。数据提取包括 T1 和 T2 时的高密度脂蛋白胆固醇（HDL）、甘油三酯（TG）、空腹血糖（FBG）、腰围（WC）、收缩压（SBP）和舒张压（DBP），MetS z 分数根据国际糖尿病联合会的标准计算。T1 时，HDL、TG、FBG、WC、SBP、DBP 和 MAP 的合并估计值分别为 1.20 [1.13；1.27] mmol/L、1.32 [1.23；1.42] mmol/L、4.98 [4.82；5.15] mmol/L、87.21 [84.21；90.21] Cm、114.22 [101.45；126.99] mmHg、76.80 [70.12；83.47] mmHg 和 89.27 [80.56；97.98] mmHg。T2 时，HDL、TG、FBG、WC、SBP、DBP 和 MAP 的合并估计值分别为 1.24 [1.18；1.31] mmol/L、1.24 [1.14；1.34] mmol/L、4.77 [4.55；4.99] mmol/L、85.73 [82.83；88.64] Cm、109.48 [97.20；121.75] mmHg、74.43 [68.01；80.85] mmHg 和 86.11 [77.74；94.48] mmHg。MetS z 分数显示所有种族和性别在 T2 时均有改善，分别为-0.22 [-0.24；-0.01]。
结论
目前的荟萃分析表明，RF 对 MetS 成分和整体 MetS z 分数有积极影响。
PROSPERO 注册号：CRD42022329297 开放科学框架标识符：DOI 10.17605/OSF.IO/U9H7T。
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