Campos-Gaona Rómulo, Correa-Orozco Adriana, Salamanca-Carreño Arcesio, Vélez-Terranova Mauricio
Facultad de Ciencias Agropecuarias, Universidad Nacional de Colombia, Sede Palmira, Palmira 763531, Colombia.
Facultad de Medicina Veterinaria y Zootecnia, Universidad Cooperativa de Colombia, Villavicencio 500001, Colombia.
Animals (Basel). 2024 Jul 13;14(14):2056. doi: 10.3390/ani14142056.
The aim of this work was to develop a liver tissue function index during the transition period of dairy cows managed in low-tropic conditions. In two farms, twenty crossbred and synthetic native cows during the peripartum period were selected, and blood samples were taken on days -30 and -15 prepartum, the calving day, and 7, 20, 35, 50, 65, 80 and 105 days postpartum for serum metabolic tests. On each measurement day, body condition scores (BCS) and parameters on nitrogen metabolism (total protein-TP, albumin-ALB, globulin-GLOB, urea), adipose tissue metabolism (cholesterol-COL, non-esterified fatty acids-NEFA) and two transaminases (alanine aminotransferase-ALT and aspartate aminotransferase-AST) were evaluated. Data analysis included the Spearman correlation, principal components, multiple linear regression and cluster analysis. Results showed that regarding the days after calving and BCS, a liver tissue function index can be constructed using the TP, urea, COL, ALT and NEFA. The estimated index generated three groupings, both by days after calving and BCS. In the former, the index discriminated the metabolic behavior in the prepartum, parturition and postpartum periods, while in the latter, the index discriminated between extreme (2.25, 2.50 and 4.25), slightly low (2.75 and 3.0) and slightly high (3.25 to 4) conditions. The results allow us to conclude that it is feasible to construct mathematical function indexes for liver function to monitor metabolic changes during highly demanding productive phases in dairy cows under tropical conditions.
这项工作的目的是制定处于低热带条件管理下的奶牛过渡期肝脏组织功能指数。在两个农场中，选取了20头围产期的杂交和本地合成奶牛，在产前30天和15天、产犊日以及产后7天、20天、35天、50天、65天、80天和105天采集血样进行血清代谢测试。在每个测量日，评估体况评分（BCS）以及氮代谢参数（总蛋白-TP、白蛋白-ALB、球蛋白-GLOB、尿素）、脂肪组织代谢参数（胆固醇-COL、非酯化脂肪酸-NEFA）和两种转氨酶（丙氨酸转氨酶-ALT和天冬氨酸转氨酶-AST）。数据分析包括Spearman相关性分析、主成分分析、多元线性回归分析和聚类分析。结果表明，关于产犊后天数和BCS，可使用TP、尿素、COL、ALT和NEFA构建肝脏组织功能指数。估计的指数按产犊后天数和BCS产生了三个分组。在前一种情况下，该指数区分了产前、分娩期和产后的代谢行为，而在后一种情况下，该指数区分了极端（2.25、2.50和4.25）、略低（2.75和3.0）和略高（3.25至4）的状况。结果使我们能够得出结论，构建肝脏功能数学函数指数以监测热带条件下奶牛高需求生产阶段的代谢变化是可行的。
