Godaert Lidvine, Dramé Moustapha
EpiCliV Research Unit, Faculty of Medicine, University of the West Indies, Fort-de-France 97261, Martinique.
General Hospital of Valenciennes-Valenciennes Hospital, Department of Supportive Care in Oncology, 114 Avenue Desandrouin, F-59300 Valenciennes, France.
Biomedicines. 2024 Jun 25;12(7):1409. doi: 10.3390/biomedicines12071409.
The aim was to determine whether there is any available evidence on the efficacy of photobiomodulation therapy (PBMT) in older adults.
A literature search was performed including all articles published up to February 2024. Studies reporting data on PBMT in older adults were included. This study was registered with PROSPERO.
In total, 406 studies were identified. After eliminating duplicates and irrelevant studies, 10 records were included in the final review. In all included studies, the protocols used to deliver PBMT were different in terms of type of device, wavelength, irradiation duration, and pulse frequency. In neurodegenerative diseases, two studies reported non-significant results, while two studies reported efficacy of PBMT. In wounds and ulcers, two out of three studies reported efficacy of PBMT. In macular degeneration, one study reported efficacy of PBMT. One study on hyposalivation reported efficacy of PBMT.
PBMT appears to be a promising complementary treatment. All studies reported good compliance and safety throughout the treatment. In the future, it will be essential to harmonize PBMT parameters. Further studies are warranted to define the best indications, the most effective protocols, and the right population to target for use in routine practice.
目的是确定是否有关于光生物调节疗法(PBMT)对老年人疗效的现有证据。
进行了文献检索,包括截至2024年2月发表的所有文章。纳入了报告老年人PBMT数据的研究。本研究已在国际前瞻性系统评价注册库(PROSPERO)登记。
共识别出406项研究。在剔除重复和不相关研究后,最终综述纳入了10篇记录。在所有纳入研究中,用于实施PBMT的方案在设备类型、波长、照射持续时间和脉冲频率方面均有所不同。在神经退行性疾病方面,两项研究报告结果无统计学意义,而两项研究报告了PBMT的疗效。在伤口和溃疡方面,三项研究中有两项报告了PBMT的疗效。在黄斑变性方面,一项研究报告了PBMT的疗效。一项关于唾液分泌减少的研究报告了PBMT的疗效。
PBMT似乎是一种有前景的辅助治疗方法。所有研究均报告在整个治疗过程中依从性良好且安全。未来,统一PBMT参数至关重要。有必要进行进一步研究以确定最佳适应症、最有效的方案以及常规实践中合适的目标人群。