Guevara Tirado Oswaldo A, Mertiri Livja, Kralik Stephen F, Desai Nilesh K, Huisman Thierry A G M, Lequin Maarten H, Tran Huy Brandon D
Ponce Health Sciences University School of Medicine, 388 Zona Industrial Reparada 2, Ponce, PR 00716, USA.
Edward B. Singleton Department of Radiology, Texas Children's Hospital and Baylor College of Medicine, 6701 Fannin Street, Suite 470, Houston, TX 77030, USA.
Children (Basel). 2024 Jun 24;11(7):763. doi: 10.3390/children11070763.
Arachnoid granulations (AGs) are generally benign structures within the subarachnoid space that extend into the dural sinuses and calvarial bone. They can present in a variety of sizes but are termed 'giant' arachnoid granulations (GAGs) when they are larger than 1 cm in diameter or take up a significant portion of the dural sinus' lumen. Vermiform giant arachnoid granulations are a specific type of GAG that are known for their worm-like appearance. Specifically, these vermiform GAGs can be challenging to diagnose as they can mimic other pathologies like dural sinus thrombosis, sinus cavernomas, or brain tumors. In this case series, we present two cases of vermiform giant arachnoid granulations, discuss their imaging characteristics and highlight the diagnostic challenges to improve identification and prevent misdiagnoses.
蛛网膜颗粒(AGs)通常是蛛网膜下腔内的良性结构,延伸至硬脑膜窦和颅骨。它们大小各异,但直径大于1厘米或占据硬脑膜窦管腔相当一部分时,就被称为“巨大”蛛网膜颗粒(GAGs)。蠕虫状巨大蛛网膜颗粒是GAG的一种特殊类型,以其蠕虫样外观而闻名。具体而言,这些蠕虫状GAGs的诊断颇具挑战性,因为它们可能会模仿其他病变,如硬脑膜窦血栓形成、海绵状窦瘤或脑肿瘤。在本病例系列中,我们展示了两例蠕虫状巨大蛛网膜颗粒病例,讨论了它们的影像学特征,并强调了诊断挑战,以提高识别率并防止误诊。