• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Continuous Infusion of Dexmedetomidine for Maintenance of Sedation in an Aggressive Adolescent with Autism Spectrum Disorder in the Emergency Department.在急诊科对一名患有自闭症谱系障碍的攻击性青少年持续输注右美托咪定以维持镇静
Children (Basel). 2024 Jul 9;11(7):833. doi: 10.3390/children11070833.
2
Dexmedetomidine in the emergency department: assessing safety and effectiveness in difficult-to-sedate acute behavioural disturbance.急诊科中右美托咪定的应用:评估在难以镇静的急性行为障碍中的安全性和有效性。
Emerg Med J. 2012 Nov;29(11):915-8. doi: 10.1136/emermed-2011-200849. Epub 2011 Dec 8.
3
Intranasal Dexmedetomidine increases the successful sedation of children with autism for out-patient auditory brainstem response hearing tests.鼻内给予右美托咪定可提高自闭症儿童在门诊进行听性脑干反应听力测试时的镇静成功率。
Int J Pediatr Otorhinolaryngol. 2021 Dec;151:110945. doi: 10.1016/j.ijporl.2021.110945. Epub 2021 Oct 19.
4
Intranasal Dexmedetomidine Use in Pediatric Patients for Anxiolysis in the Emergency Department.鼻内应用右美托咪定在急诊科用于儿科患者的焦虑缓解。
Pediatr Emerg Care. 2023 Sep 1;39(9):685-691. doi: 10.1097/PEC.0000000000002901. Epub 2023 Jan 5.
5
[A study of using dexmedetomidine in ventilator bundle treatment in an ICU].[右美托咪定在重症监护病房呼吸机集束治疗中的应用研究]
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2015 Oct;27(10):836-40.
6
Dexmedetomidine use in the ED for control of methamphetamine-induced agitation.在急诊科使用右美托咪定控制甲基苯丙胺所致躁动。
Am J Emerg Med. 2017 Apr;35(4):665.e1-665.e4. doi: 10.1016/j.ajem.2016.11.004. Epub 2016 Nov 3.
7
Successful use of dexmedetomidine for sedation in a 24-week gestational age neonate.右美托咪定成功用于一名孕24周新生儿的镇静。
Ann Pharmacother. 2009 Oct;43(10):1707-13. doi: 10.1345/aph.1M245. Epub 2009 Sep 15.
8
Procedural Sedation With Dexmedetomidine in Combination With Ketamine in the Emergency Department.急诊科中用右美托咪定联合氯胺酮进行的程序性镇静。
J Emerg Med. 2022 Aug;63(2):283-289. doi: 10.1016/j.jemermed.2022.01.017. Epub 2022 May 9.
9
Dexmedetomidine for procedural sedation in children with autism and other behavior disorders.右美托咪定用于自闭症及其他行为障碍儿童的程序性镇静。
Pediatr Neurol. 2009 Aug;41(2):88-94. doi: 10.1016/j.pediatrneurol.2009.02.006.
10
Use of dexmedetomidine for prophylactic analgesia and sedation in delayed extubation patients after craniotomy: a study protocol and statistical analysis plan for a randomized controlled trial.右美托咪定用于开颅术后延迟拔管患者预防性镇痛和镇静的研究:一项随机对照试验的研究方案和统计分析计划
Trials. 2013 Aug 13;14:251. doi: 10.1186/1745-6215-14-251.

引用本文的文献

1
Association between anesthetics and autism spectrum disorder: from bench to bedside.麻醉剂与自闭症谱系障碍之间的关联:从实验室到临床
J Anesth. 2025 Jun 2. doi: 10.1007/s00540-025-03519-5.

本文引用的文献

1
Approach to acute agitation in the pediatric emergency department.儿科急诊急性激越的处理方法。
Curr Opin Pediatr. 2024 Jun 1;36(3):245-250. doi: 10.1097/MOP.0000000000001337. Epub 2024 Jan 31.
2
A Rapid Systematic Review of Pharmacologic Sleep Promotion Modalities in the Intensive Care Unit.重症监护病房中药物促进睡眠的各种模式的快速系统评价。
J Intensive Care Med. 2024 Jan;39(1):28-43. doi: 10.1177/08850666231186747. Epub 2023 Jul 4.
3
Acute Severe Behavioral Disturbance Requiring Parenteral Sedation in Pediatric Mental Health Presentations to Emergency Medical Services: A Retrospective Chart Review.儿科心理健康患者因急性严重行为障碍需经胃肠外途径镇静并前往紧急医疗服务机构就诊的回顾性病历审查
Ann Emerg Med. 2023 Nov;82(5):546-557. doi: 10.1016/j.annemergmed.2023.04.028. Epub 2023 Jun 30.
4
Safety and Efficacy Associated With a Family-Centered Procedural Sedation Protocol for Children With Autism Spectrum Disorder or Developmental Delay.与以家庭为中心的程序镇静方案相关的自闭症谱系障碍或发育迟缓儿童的安全性和有效性。
JAMA Netw Open. 2023 May 1;6(5):e2315974. doi: 10.1001/jamanetworkopen.2023.15974.
5
Intranasal Dexmedetomidine: Should It Have a Place in Your Emergency Department?鼻内用右美托咪定:它在急诊科是否应有一席之地?
Ann Emerg Med. 2023 Aug;82(2):191-193. doi: 10.1016/j.annemergmed.2023.02.022. Epub 2023 Apr 12.
6
Behavioral Management of Children With Autism in the Emergency Department.急诊科自闭症儿童的行为管理。
Pediatr Emerg Care. 2023 Jan 1;39(1):45-50. doi: 10.1097/PEC.0000000000002886.
7
Dexmedetomidine: What's New for Pediatrics? A Narrative Review.右美托咪定:儿科领域有哪些新进展?一篇叙述性综述。
J Clin Med. 2020 Aug 24;9(9):2724. doi: 10.3390/jcm9092724.
8
Intramuscular Dexmedetomidine, a Feasible Option for Children With Autism Spectrum Disorders Needing Urgent Procedural Sedation.肌肉注射右美托咪定,是需要紧急程序性镇静的自闭症谱系障碍儿童的可行选择。
Pediatr Emerg Care. 2019 Jun;35(6):e116-e117. doi: 10.1097/PEC.0000000000001776.
9
Procedural sedation in children with autism spectrum disorders in the emergency department.急诊科孤独症谱系障碍儿童的程序性镇静。
Am J Emerg Med. 2019 Aug;37(8):1404-1408. doi: 10.1016/j.ajem.2018.10.025. Epub 2018 Oct 16.
10
A Comparison of Safety and Efficacy of Dexmedetomidine and Propofol in Children with Autism and Autism Spectrum Disorders Undergoing Magnetic Resonance Imaging.右美托咪定和丙泊酚在孤独症和孤独症谱系障碍儿童磁共振成像中安全性和疗效的比较。
J Autism Dev Disord. 2018 Sep;48(9):3127-3132. doi: 10.1007/s10803-018-3582-1.

在急诊科对一名患有自闭症谱系障碍的攻击性青少年持续输注右美托咪定以维持镇静

Continuous Infusion of Dexmedetomidine for Maintenance of Sedation in an Aggressive Adolescent with Autism Spectrum Disorder in the Emergency Department.

作者信息

Cozzi Giorgio, Zago Alessandro, Poropat Federico, Rabach Ingrid, Barbi Egidio, Amaddeo Alessandro

机构信息

Institute for Maternal and Child Health-IRCCS "Burlo Garofolo", 34137 Trieste, Italy.

Department of Medicine, Surgery and Health Sciences, University of Trieste, 34127 Trieste, Italy.

出版信息

Children (Basel). 2024 Jul 9;11(7):833. doi: 10.3390/children11070833.

DOI:10.3390/children11070833
PMID:39062282
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11276318/
Abstract

BACKGROUND

The treatment of aggressive behavior and agitation in pediatric patients with autism spectrum disorder (ASD) in the emergency department is topical and challenging.

CASE PRESENTATION

We described an adolescent with autism spectrum disorder treated ten times in the pediatric emergency department for severe episodes of aggressiveness and agitation. After resolving the acute phase of these behavioural crises, sedation was maintained with a continuous infusion of dexmedetomidine to prevent the resurgence of agitation and to organize discharge properly, considering the family's needs. The continuous infusion of dexmedetomidine allowed the patient to remain asleep most of the time during his stay at the emergency department. No adverse events were recorded.

CONCLUSIONS

The continuous infusion of dexmedetomidine could represent a safe and valuable tool to facilitate the permanence of the patient in the PED.

摘要

背景

急诊部门对患有自闭症谱系障碍(ASD)的儿科患者攻击性行为和激越的治疗是热门且具有挑战性的。

病例介绍

我们描述了一名患有自闭症谱系障碍的青少年,因严重的攻击和激越发作在儿科急诊科接受了10次治疗。在解决这些行为危机的急性期后,考虑到家庭需求,通过持续输注右美托咪定维持镇静,以防止激越复发并妥善安排出院。在患者留观急诊科期间,持续输注右美托咪定使患者大部分时间处于睡眠状态。未记录到不良事件。

结论

持续输注右美托咪定可能是促进患者在儿科急诊室留观的一种安全且有价值的工具。