Division of Microbiology, Faculty of Biology, Ludwig-Maximilians-Universität München, 82152 Martinsried, Germany.
Department of Chemical Sciences, University of Napoli Federico II, Complesso Universitario Monte Sant'Angelo, 80126 Napoli, Italy.
Int J Mol Sci. 2024 Jul 13;25(14):7685. doi: 10.3390/ijms25147685.
Extremophilic microorganisms play a key role in understanding how life on Earth originated and evolved over centuries. Their ability to thrive in harsh environments relies on a plethora of mechanisms developed to survive at extreme temperatures, pressures, salinity, and pH values. From a biotechnological point of view, thermophiles are considered a robust tool for synthetic biology as well as a reliable starting material for the development of sustainable bioprocesses. This review discusses the current progress in the biomanufacturing of high-added bioproducts from thermophilic microorganisms and their industrial applications.
极端微生物在理解地球生命的起源和数世纪以来的演化方面发挥着关键作用。它们在恶劣环境中茁壮成长的能力依赖于大量发展起来的机制,这些机制旨在耐受极端温度、压力、盐度和 pH 值。从生物技术的角度来看,嗜热菌被认为是合成生物学的有力工具,也是开发可持续生物工艺的可靠起始材料。本文综述了从嗜热微生物生物制造高附加值生物制品及其工业应用的最新进展。