Kryczyk-Kozioł Jadwiga, Moniak Paulina, Zagrodzki Paweł, Lauterbach Ryszard, Huras Hubert, Staśkiewicz Magdalena, Krośniak Mirosław, Paśko Paweł, Podsiadły Robert, Dobrowolska-Iwanek Justyna
Department of Food Chemistry and Nutrition, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland.
Department of Neonatology, Jagiellonian University Hospital, Kopernika 23, 31-501 Kraków, Poland.
Foods. 2024 Jul 16;13(14):2241. doi: 10.3390/foods13142241.
Considering the spectrum of benefits of breast milk feeding, determining the essential components of an infant's only food-mother's milk-seems justified, especially in the case of those whose deficiency (e.g., iodine) may result in developmental disorders. The main aim of this study was the determination of the total iodine content of breast milk (including colostrum and mature milk). A secondary objective was to assess the influence of factors such as the type of delivery, hypothyroidism, gestational diabetes or the stage of lactation on this parameter. The study materials were colostrum and milk after 1 ( = 14), 2 and 3 months ( = 8) of lactation with a range of iodine concentrations (µg/L): 195-1648 and 170-842, 174-650 and 273-751, respectively. Iodine was determined using the inductively coupled plasma mass spectrometry (ICP-MS). Multivariate statistical analysis revealed, e.g., that delivery by caesarean section or dose of L-thyroxine taken by women to normalise thyroid hormones, had a significant effect on iodine concentrations in breast milk. Further research aimed at assessing the quality of breast milk should also include determining the factors influencing it.
考虑到母乳喂养的诸多益处，确定婴儿唯一食物——母乳的必需成分似乎是合理的，尤其是对于那些缺乏某种成分（如碘）可能导致发育障碍的情况。本研究的主要目的是测定母乳（包括初乳和成熟乳）中的总碘含量。次要目的是评估分娩方式、甲状腺功能减退、妊娠期糖尿病或哺乳阶段等因素对该参数的影响。研究材料为产后1个月（=14天）、2个月和3个月（=8个月）的初乳和乳汁，碘浓度范围（μg/L）分别为：195 - 1648、170 - 842、174 - 650和273 - 751。使用电感耦合等离子体质谱法（ICP-MS）测定碘含量。多变量统计分析表明，例如剖宫产分娩或女性为使甲状腺激素正常化而服用的L-甲状腺素剂量，对母乳中的碘浓度有显著影响。旨在评估母乳质量的进一步研究也应包括确定影响母乳质量的因素。
