Liu Mengpei, Wang Yan, Wang Rong, Zong Wei, Zhang Lihua, Wang Lu
Key Laboratory of Cold Chain Food Processing and Safety Control, Ministry of Education, College of Food and Bioengineering, Zhengzhou University of Light Industry, Zhengzhou 450001, China.
State Key Laboratory of Tree Genetics and Breeding, Key Laboratory of Non-Timber Forest Germplasm Enhancement & Utilization of State Administration of Forestry and Grassland, Research Institute of Non-Timber Forestry, Chinese Academy of Forestry, Zhengzhou 450003, China.
Foods. 2024 Jul 22;13(14):2302. doi: 10.3390/foods13142302.
An innovative iron supplement crucial for treating iron-deficiency anemia was developed in this study. Polysaccharide was extracted from leaves using a microwave-assisted hot water method, and subsequently, the polysaccharide-iron complex was synthesized through co-thermal synthesis with FeCl. The physicochemical properties, structure, and thermal stability of the complex were analyzed using FE-SEM, SEC-MALLS, FT-IR, XRD, and DSC techniques. Furthermore, the antioxidant activity of the polysaccharide-iron complex was evaluated through an experiment in vitro. The results revealed that the polysaccharide-iron complex had an iron content of 6.1% and an average particle size of 860.4 nm. The microstructure analysis indicated that the polysaccharide-iron complex possessed a flaky morphology with smooth and compact surfaces. Moreover, the formation of the Fe complex did not alter the structural framework of the polysaccharide; instead, it enhanced the polysaccharide's thermal stability. Compared to traditional iron supplements, the -derived polysaccharide-iron complex demonstrated significant antioxidant activity. Therefore, this novel compound exhibits significant potential as a viable iron supplement.
本研究开发了一种治疗缺铁性贫血的创新型铁补充剂。采用微波辅助热水法从树叶中提取多糖,随后通过与FeCl进行共热合成制备多糖铁复合物。利用场发射扫描电子显微镜(FE-SEM)、多角度激光光散射凝胶渗透色谱(SEC-MALLS)、傅里叶变换红外光谱(FT-IR)、X射线衍射(XRD)和差示扫描量热法(DSC)技术对该复合物的物理化学性质、结构和热稳定性进行了分析。此外,通过体外实验评估了多糖铁复合物的抗氧化活性。结果表明,多糖铁复合物的铁含量为6.1%,平均粒径为860.4 nm。微观结构分析表明,多糖铁复合物具有片状形态,表面光滑致密。此外,铁复合物的形成并未改变多糖的结构框架,反而增强了多糖的热稳定性。与传统铁补充剂相比,该树叶来源的多糖铁复合物具有显著的抗氧化活性。因此,这种新型化合物作为一种可行的铁补充剂具有巨大潜力。