Khalafi Shayan, Botero Fonnegra Cristina, Reyes Ana, Hui Vanessa W
DeWitt Daughtry Family Department of Surgery, Division of Colon & Rectal Surgery, Miller School of Medicine, University of Miami, Miami, FL 33130, USA.
J Clin Med. 2024 Jul 9;13(14):4003. doi: 10.3390/jcm13144003.
Indocyanine Green (ICG) has significantly advanced minimally invasive surgery. It is widely recognized for its ability to visualize blood vessel patency in real-time across various surgical specialties. While its primary use in colorectal surgery is to evaluate anastomoses for leaks, numerous other applications have been documented in the literature. In this review, we aim to explore both established and emerging applications of ICG fluorescence in colorectal surgery, with the goal of improving patient outcomes. This includes preoperative tumor marking and the detection of metastatic disease. Some applications, such as lymphatic mapping, require further research to determine their impact on clinical practices. Conversely, others, like the intraoperative localizations of ureters, necessitate additional procedures and are not yet widely accepted by the surgical community. However, the development of alternative compounds could offer better solutions. Future research should focus on areas like quantitative ICG and protocol standardization in prospective multicenter studies.
吲哚菁绿（ICG）极大地推动了微创手术的发展。它能够在实时可视化各种外科专业手术中的血管通畅情况，这一点得到了广泛认可。虽然其在结直肠手术中的主要用途是评估吻合口是否漏血，但文献中还记载了许多其他应用。在本综述中，我们旨在探讨ICG荧光在结直肠手术中的既定应用和新兴应用，以期改善患者预后。这包括术前肿瘤标记和转移性疾病的检测。一些应用，如淋巴管造影，需要进一步研究以确定其对临床实践的影响。相反，其他一些应用，如术中输尿管定位，则需要额外的操作，尚未被外科界广泛接受。然而，开发替代化合物可能会提供更好的解决方案。未来的研究应集中在前瞻性多中心研究中的定量ICG和方案标准化等领域。
