Wu Kevin Y, Dave Archan, Carbonneau Marjorie, Tran Simon D
Department of Surgery, Division of Ophthalmology, University of Sherbrooke, Sherbrooke, QC J1G 2E8, Canada.
Department of Medicine, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Micromachines (Basel). 2024 Jun 30;15(7):856. doi: 10.3390/mi15070856.
Smart contact lenses represent a breakthrough in the intersection of medical science and innovative technology, offering transformative potential in ophthalmology. This review article delves into the technological underpinnings of smart contact lenses, emphasizing the current landscape and advancements in biosensors, power supply, biomaterials, and the transmission of ocular information. This review further applies new innovations to their emerging role in the diagnosis, monitoring, and management of various ocular conditions. Moreover, we explore the impact of technical innovations on the application of smart contact lenses in monitoring glaucoma, managing postoperative care, and dry eye syndrome, further elucidating the non-invasive nature of these devices in continuous ocular health monitoring. The therapeutic potential of smart contact lenses such as treatment through targeted drug delivery and the monitoring of inflammatory biomarkers is also highlighted. Despite promising advancements, the implementation of smart contact lenses faces technical, regulatory, and patient compliance challenges. This review synthesizes the recent advances to provide an outlook on the state of smart contact lens technology. Furthermore, we discuss future directions, focusing on potential technological enhancements and new applications within ophthalmology.
智能隐形眼镜代表了医学科学与创新技术交叉领域的一项突破，在眼科领域具有变革潜力。这篇综述文章深入探讨了智能隐形眼镜的技术基础，重点介绍了生物传感器、电源、生物材料以及眼部信息传输方面的当前现状和进展。本综述进一步将新创新应用于其在各种眼部疾病的诊断、监测和管理中的新兴作用。此外，我们探讨了技术创新对智能隐形眼镜在青光眼监测、术后护理管理和干眼症综合征应用中的影响，进一步阐明了这些设备在持续眼部健康监测中的非侵入性本质。还强调了智能隐形眼镜的治疗潜力，如通过靶向药物递送进行治疗和监测炎症生物标志物。尽管取得了令人鼓舞的进展，但智能隐形眼镜的实施面临技术、监管和患者依从性方面的挑战。本综述综合了近期进展，以展望智能隐形眼镜技术的现状。此外，我们讨论了未来方向，重点关注眼科领域潜在的技术改进和新应用。
