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羟基磷灰石-磷酸三钙涂层全髋关节置换术(Trilogy/Zimmer)的长期结果和影像学评估:一项长期随访研究。

Long-Term Outcomes and a Radiological Assessment of Hydroxyapatite-Tricalcium Phosphate-Coated Total Hip Arthroplasty (Trilogy/Zimmer): A Long-Term Follow-Up Study.

机构信息

Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510, Japan.

Department of Orthopedic Surgery, Uonuma Kikan Hospital, Niigata 949-7302, Japan.

出版信息

Medicina (Kaunas). 2024 Jul 17;60(7):1154. doi: 10.3390/medicina60071154.

Abstract

Favorable short- and mid-term results for hydroxyapatite (HA)-tricalcium phosphate (TCP)-coated total hip arthroplasty (THA) (Trilogy/Zimmer) have been reported in the literature; however, the long-term results beyond 15 years have not been documented. Therefore, this study evaluated the long-term postoperative results, radiological bone changes, and implant fixation of the acetabular component of HA-TCP-coated THA. This is a retrospective cohort study of 212 patients who underwent primary HA-TCP-coated THA (Trilogy/Zimmer) at our institution between 1 October 2002, and 31 March 2008; 166 who were available for follow-up at least 15 years postoperatively were included (capture rate: 78.3%). All implants were Trilogy/Zimmer. We investigated the survival rate, with aseptic loosening as the endpoint. Clinical evaluations included the presence of dislocation and a modified Harris Hip Score (mHHS) preoperatively and at the final observation. The mean age at surgery and at the follow-up period were 57.7 ± 9.6 and 17.1 ± 1.5 years, respectively. The survival rate was 99.4% (165/166), with aseptic loosening as the endpoint. Dislocation was observed in 4/166 (2.4%) patients. The mHHS improved significantly from 46.1 points preoperatively to 82.2 points during the last survey ( < 0.05). The results revealed that fixation was favorable in all cases except for one case of aseptic loosening. The Trilogy implant coated with HA-TCP was highly effective in bone induction, and bone ingrowth was considered to have occurred without failure, further indicating its usefulness. The long-term results of cementless THA using an HA-TCP coating (Trilogy/Zimmer), with a mean follow-up period of 17.1 years, revealed a commendable survival rate of 99.4%, considering aseptic loosening as the endpoint. HA-TCP-coated THA (Trilogy/Zimmer) had good long-term results. However, further long-term observation is required in patients who have undergone this surgery, and the stem side should be evaluated and investigated, including comorbidities.

摘要

羟基磷灰石(HA)-磷酸三钙(TCP)涂层全髋关节置换术(THA)(Trilogy/Zimmer)在文献中报道了短期和中期的良好结果;然而,15 年以上的长期结果尚未记录。因此,本研究评估了 HA-TCP 涂层 THA 的髋臼部件的长期术后结果、放射学骨变化和植入物固定。 这是一项回顾性队列研究,纳入了 212 例于 2002 年 10 月 1 日至 2008 年 3 月 31 日在我院行初次 HA-TCP 涂层 THA(Trilogy/Zimmer)的患者;166 例至少在术后 15 年时可随访(捕获率:78.3%)。所有植入物均为 Trilogy/Zimmer。我们调查了以无菌性松动为终点的生存率。临床评估包括术前和最后一次观察时的脱位情况和改良 Harris 髋关节评分(mHHS)。 手术时和随访时的平均年龄分别为 57.7 ± 9.6 岁和 17.1 ± 1.5 岁。以无菌性松动为终点的生存率为 99.4%(165/166)。4/166(2.4%)患者发生脱位。mHHS 从术前的 46.1 分显著改善至末次调查的 82.2 分(<0.05)。结果表明,除 1 例无菌性松动外,所有病例的固定均良好。HA-TCP 涂层的 Trilogy 植入物在骨诱导方面非常有效,骨长入被认为是成功的,进一步表明其有用性。HA-TCP 涂层(Trilogy/Zimmer)非骨水泥 THA 的长期结果,平均随访 17.1 年,以无菌性松动为终点,生存率为 99.4%,结果令人赞赏。 HA-TCP 涂层 THA(Trilogy/Zimmer)具有良好的长期结果。然而,需要对接受这种手术的患者进行进一步的长期观察,并应评估和研究包括合并症在内的干侧。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c9e/11278935/8b8b73fb2ebb/medicina-60-01154-g001.jpg

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