Department of Internal Medicine and Medical Specialties, University of Genoa, Viale Benedetto XV 6, 16132 Genoa, Italy.
IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi 10, 16132 Genoa, Italy.
Nutrients. 2024 Jul 13;16(14):2262. doi: 10.3390/nu16142262.
There is currently a growing interest in diets and physical activity patterns that may be beneficial in preventing and treating breast cancer (BC). Mounting evidence indicates that indeed, the so-called Mediterranean diet (MedDiet) and regular physical activity likely both help reduce the risk of developing BC. For those who have already received a BC diagnosis, these interventions may decrease the risk of tumor recurrence after treatment and improve quality of life. Studies also show the potential of other dietary interventions, including fasting or modified fasting, calorie restriction, ketogenic diets, and vegan or plant-based diets, to enhance the efficacy of BC therapies. In this review article, we discuss the biological rationale for utilizing these dietary interventions and physical activity in BC prevention and treatment. We highlight published and ongoing clinical studies that have applied these lifestyle interventions to BC patients. This review offers valuable insights into the potential application of these dietary interventions and physical activity as complimentary therapies in BC management.
目前,人们对可能有助于预防和治疗乳腺癌 (BC) 的饮食和身体活动模式越来越感兴趣。越来越多的证据表明,所谓的地中海饮食 (MedDiet) 和有规律的身体活动确实有助于降低患 BC 的风险。对于那些已经被诊断出患有 BC 的人来说,这些干预措施可能会降低治疗后肿瘤复发的风险,并提高生活质量。研究还表明,其他饮食干预措施,包括禁食或改良禁食、热量限制、生酮饮食以及纯素或植物性饮食,也有可能增强 BC 治疗的效果。在这篇综述文章中,我们讨论了利用这些饮食干预措施和身体活动来预防和治疗 BC 的生物学依据。我们强调了已经将这些生活方式干预应用于 BC 患者的已发表和正在进行的临床研究。这篇综述为这些饮食干预措施和身体活动作为 BC 管理的补充疗法的潜在应用提供了有价值的见解。