Daymond T J, Thompson M, Akbar F A, Chestney V
Rheumatol Rehabil. 1979 Nov;18(4):257-60. doi: 10.1093/rheumatology/18.4.257.
Tiaprofenic acid, 200 mg three times a day, was compared with ibuprofen, 400 mg three times a day, in 41 patients suffering from rheumatoid arthritis and already receiving nonsteroidal anti-inflammatory drugs in a double-blind controlled study. The degree of disability expressed as functional class was significantly improved on tiaprofenic acid. There were no other significant differences from initial values on either treatment in any other clinical measure of therapeutic efficacy. Side-effects were few and minor and there were no significant differences between the drugs in this respect.
在一项双盲对照研究中，对41名类风湿性关节炎患者且已在服用非甾体抗炎药的患者，比较了每天三次服用200毫克噻洛芬酸与每天三次服用400毫克布洛芬的效果。以功能分级表示的残疾程度在服用噻洛芬酸后有显著改善。在任何其他治疗效果的临床指标方面，两种治疗方法与初始值相比均无其他显著差异。副作用少且轻微，在这方面两种药物之间没有显著差异。
