School of Control Science and Engineering, Shandong University, Jinan City, Shandong Province, 250061, China.
Department of Urology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, 250014, China.
Photodiagnosis Photodyn Ther. 2024 Aug;48:104292. doi: 10.1016/j.pdpdt.2024.104292. Epub 2024 Jul 26.
Melanocytic nevi (MN), warts, seborrheic keratoses (SK), and psoriasis are four common types of skin surface lesions that typically require dermatoscopic examination for definitive diagnosis in clinical dermatology settings. This process is labor-intensive and resource-consuming. Traditional methods for diagnosing skin lesions rely heavily on the subjective judgment of dermatologists, leading to issues in diagnostic accuracy and prolonged detection times.
This study aims to introduce a multispectral imaging (MSI)-based method for the early screening and detection of skin surface lesions. By capturing image data at multiple wavelengths, MSI can detect subtle spectral variations in tissues, significantly enhancing the differentiation of various skin conditions.
The proposed method utilizes a pixel-level mosaic imaging spectrometer to capture multispectral images of lesions, followed by reflectance calibration and standardization. Regions of interest were manually extracted, and the spectral data were subsequently exported for analysis. An improved one-dimensional convolutional neural network is then employed to train and classify the data.
The new method achieves an accuracy of 96.82 % on the test set, demonstrating its efficacy.
This multispectral imaging approach provides a non-contact and non-invasive method for early screening, effectively addressing the subjective identification of lesions by dermatologists and the prolonged detection times associated with conventional methods. It offers enhanced diagnostic accuracy for a variety of skin lesions, suggesting new avenues for dermatological diagnostics.
黑素细胞痣(MN)、疣、脂溢性角化病(SK)和银屑病是皮肤科中四种常见的皮肤表面病变类型,通常需要进行皮肤镜检查以明确诊断。这是一个劳动密集型和资源密集型的过程。传统的皮肤病变诊断方法主要依赖皮肤科医生的主观判断,导致诊断准确性和检测时间延长等问题。
本研究旨在介绍一种基于多光谱成像(MSI)的皮肤表面病变早期筛查和检测方法。MSI 通过在多个波长下捕获图像数据,可以检测到组织中的细微光谱变化,显著提高了各种皮肤状况的区分能力。
该方法使用像素级马赛克成像光谱仪捕获病变的多光谱图像,然后进行反射率校准和标准化。手动提取感兴趣区域,并导出光谱数据进行分析。然后,采用改进的一维卷积神经网络对数据进行训练和分类。
新方法在测试集上的准确率达到 96.82%,证明了其有效性。
这种多光谱成像方法提供了一种非接触、非侵入性的早期筛查方法,有效解决了皮肤科医生对病变的主观识别和传统方法检测时间长的问题。它为各种皮肤病变提供了更高的诊断准确性,为皮肤科诊断开辟了新的途径。