Department of Medical Virology, Basaksehir Cam and Sakura City Hospital, University of Health Sciences, Istanbul, Turkey.
Department of Infectious Diseases and Clinical Microbiology, Basaksehir Cam and Sakura City Hospital, University of Health Sciences, Istanbul, Turkey.
Cent Eur J Public Health. 2024 Jun;32(2):125-131. doi: 10.21101/cejph.a7981.
Measles cases are increasing remarkably in our country as well as all over the world. In this study, it was aimed to examine the epidemiological and clinical characteristics of measles cases detected in our hospital, as well as the measles seroprevalence in our region.
A total of 7,452 individuals whose measles IgG and/or IgM antibodies were studied between December 2021 and March 2023 in the Medical Virology Laboratory in Başakşehir Çam and Sakura City Hospital were included in this retrospective study. Measles IgG and IgM antibodies were analysed by enzyme-linked immunosorbent assay. Demographic information, clinical symptoms and laboratory data of the participants were obtained from the hospital's electronic medical records.
A total of 102 measles cases were identified between December 2021 and March 2023. Of these cases, 77 (75.5%) patients were ≤ 18 years old. Of the 73 measles cases with vaccination information, 90% were unvaccinated. The measles seroprevalence rate was 72.8%. The lowest seroprevalence rate (4.8%) among the age groups was found in 8-11-month-old babies, the highest cases rate (35.7%) was detected in this age group. It was determined that measles immunity increased with age (r = 0.276, p < 0.001) and was over 89.3% over the age of 30.
Measles immunity is insufficient in our region and measles remains an important public health problem until the age of 18. The recent increase in measles cases in our country and around the world shows that current vaccination programmes need to be implemented more decisively and strictly.
麻疹病例在我国乃至全球均显著增加。本研究旨在探讨我院检出麻疹病例的流行病学和临床特征,以及本地区麻疹血清流行率。
本回顾性研究纳入了 2021 年 12 月至 2023 年 3 月在 Başakşehir Çam 和 Sakura 城市医院医学病毒学实验室检测麻疹 IgG 和/或 IgM 抗体的 7452 名个体。采用酶联免疫吸附试验分析麻疹 IgG 和 IgM 抗体。从医院的电子病历中获取参与者的人口统计学信息、临床症状和实验室数据。
2021 年 12 月至 2023 年 3 月期间共发现 102 例麻疹病例。其中,77 例(75.5%)患者≤18 岁。在 73 例有疫苗接种信息的麻疹病例中,90%未接种疫苗。麻疹血清流行率为 72.8%。8-11 月龄婴儿的血清流行率最低(4.8%),该年龄组的病例率最高(35.7%)。研究确定麻疹免疫力随年龄增长而增加(r = 0.276,p < 0.001),30 岁以上者免疫力超过 89.3%。
本地区麻疹免疫力不足,麻疹仍是 18 岁以下人群的重要公共卫生问题。我国乃至全球近期麻疹病例的增加表明,当前的疫苗接种计划需要更果断和严格地实施。