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大学医院三级护理中初次肩关节置换术的高合并症负担及低不良事件发生率

High comorbidity burden and low incidence of adverse events in primary shoulder arthroplasty in tertiary care at a university hospital.

作者信息

Wolf Matthias, Goldmann Albert, Tsitlakidis Stefanos, Renkawitz Tobias, Maier Michael W, Bülhoff Matthias

机构信息

Heidelberg University Hospital, Orthopaedic University Hospital, Schlierbacher Landstraße 200a, 69118, Heidelberg, Germany.

Swabian Joint Center Backnang, Neckarsulmer Str. 5, 71522, Backnang, Germany.

出版信息

J Orthop. 2024 Jun 27;58:82-89. doi: 10.1016/j.jor.2024.06.040. eCollection 2024 Dec.

Abstract

BACKGROUND

Reducing perioperative risk is in the focus of primary arthroplasty caregivers. Primary shoulder arthroplasty patients are considered among those with the lowest perioperative risk. Nonetheless, in tertiary care centres and university settings patients with significant comorbidities are being treated. It remains unclear whether the overall comorbidity burden is truly higher and if this results in an increased frequency of adverse events (AE). As a result, we conducted a study to assess the comorbidity burden and the frequency of major perioperative adverse events and predictive factors following primary shoulder arthroplasty in the university setting.

METHODS

A retrospective cohort analysis was conducted on patients undergoing primary shoulder arthroplasty for a non-trauma, non-tumour indication from January 1st, 2014 through December 31st, 2018. Administrative data were recorded to assess comorbidity burden and revision surgery within the first postoperative year. Major adverse events were routinely recorded on a weekly basis by the treating physicians. Descriptive and comparative statistical analyses were performed. The cohort was compared against a large North American sample.

RESULTS

Of 386 patients who underwent 400 primary shoulder arthroplasties 14 (3.5 %) experienced adverse events. While AE were distributed equally among anatomical and reverse shoulder arthroplasties, no adverse event was recorded in the 34 hemiarthroplasty patients. The cohort showed an increased comorbidity burden in international comparison. Peptic ulcer disease was significantly associated with AE, while mild liver disease experienced a trend towards AE.

CONCLUSION

We found an increased comorbidity burden and a low rate of AE for primary shoulder arthroplasty in a tertiary care and university setting. The distinct role of peptic ulcer disease in this cohort and the trend in mild liver disease merit further investigation in larger samples. The findings underscore the importance of perioperative risk assessment and management.

LEVEL OF EVIDENCE

III, retrospective cohort study.

摘要

背景

降低围手术期风险是初次关节置换术医护人员关注的焦点。初次肩关节置换术患者被认为是围手术期风险最低的患者群体之一。然而,在三级医疗中心和大学环境中,患有严重合并症的患者也在接受治疗。目前尚不清楚总体合并症负担是否真的更高,以及这是否会导致不良事件(AE)发生率增加。因此,我们进行了一项研究,以评估大学环境中初次肩关节置换术后的合并症负担、主要围手术期不良事件的发生率及预测因素。

方法

对2014年1月1日至2018年12月31日因非创伤性、非肿瘤性适应证接受初次肩关节置换术的患者进行回顾性队列分析。记录管理数据以评估合并症负担和术后第一年内的翻修手术情况。主治医生每周定期记录主要不良事件。进行描述性和比较性统计分析。将该队列与一个大型北美样本进行比较。

结果

在接受400例初次肩关节置换术的386例患者中,14例(3.5%)发生了不良事件。虽然不良事件在解剖型和反肩关节置换术中分布均匀,但34例半关节置换术患者未记录到不良事件。与国际比较,该队列显示合并症负担增加。消化性溃疡病与不良事件显著相关,而轻度肝病有发生不良事件的趋势。

结论

我们发现在三级医疗和大学环境中,初次肩关节置换术的合并症负担增加,不良事件发生率较低。消化性溃疡病在该队列中的独特作用以及轻度肝病的趋势值得在更大样本中进一步研究。这些发现强调了围手术期风险评估和管理的重要性。

证据级别

III,回顾性队列研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de8a/11269281/46acc3aeab6a/gr1.jpg

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