• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

印度一名接受多价抗蛇毒血清治疗的患者在被银环蛇咬伤后出现血清病的罕见表现:病例介绍与挑战

A rare manifestation of serum sickness after common krait envenomation in a patient treated with polyvalent anti-snake venom in India: Presentation and challenges.

作者信息

Guru Satyabrata, Bellapukonda Snigda, Mohanty Chitta R, Radhakrishnan Rakesh V, Gupta Anju

机构信息

Department of Trauma and Emergency, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.

Department of Anaesthesiology, Basavatarakam Indo-American Cancer Hospital and Research Institute, Hyderabad, Telangana, India.

出版信息

J Family Med Prim Care. 2024 Jul;13(7):2792-2794. doi: 10.4103/jfmpc.jfmpc_417_23. Epub 2024 Jun 28.

DOI:10.4103/jfmpc.jfmpc_417_23
PMID:39071008
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11272001/
Abstract

Envenomation from snakebites is a significant public health concern in the Southeast Asian region resulting in considerable mortality and morbidity. Anti-snake venom (ASV) despite being the only rescue can bring forth several acute and delayed adverse effects. Among them, serum sickness is a late manifestation after treatment with ASV that presents after 5-14 days of treatment. However, there is no specific definition to diagnose serum sickness or proven treatment. Here, we present a case of serum sickness to provide an insight into this unventured zone, briefing the presentation, treatment and probable reason for serum sickness and its prevention after common krait envenomation and treatment with polyvalent ASV in India.

摘要

蛇咬伤中毒是东南亚地区一个重大的公共卫生问题,会导致相当高的死亡率和发病率。抗蛇毒血清(ASV)尽管是唯一的救治手段,但也会引发多种急性和迟发性不良反应。其中,血清病是使用ASV治疗后的一种晚期表现,在治疗5 - 14天后出现。然而,目前尚无诊断血清病的具体定义或经过验证的治疗方法。在此,我们报告一例血清病病例,以深入了解这一未知领域,介绍印度普通眼镜蛇咬伤并使用多价ASV治疗后血清病的表现、治疗、可能原因及其预防。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a19/11272001/f23b5d05d545/JFMPC-13-2792-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a19/11272001/f23b5d05d545/JFMPC-13-2792-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a19/11272001/f23b5d05d545/JFMPC-13-2792-g001.jpg

相似文献

1
A rare manifestation of serum sickness after common krait envenomation in a patient treated with polyvalent anti-snake venom in India: Presentation and challenges.印度一名接受多价抗蛇毒血清治疗的患者在被银环蛇咬伤后出现血清病的罕见表现:病例介绍与挑战
J Family Med Prim Care. 2024 Jul;13(7):2792-2794. doi: 10.4103/jfmpc.jfmpc_417_23. Epub 2024 Jun 28.
2
Serious Adverse Reactions to Anti-snake Venom in Children with Snake Envenomation: An Underappreciated Contributor to Snakebite Mortality?蛇咬伤儿童抗蛇毒血清的严重不良反应:蛇咬伤致死率的一个未被充分认识的因素?
Indian J Crit Care Med. 2021 Jun;25(6):720-723. doi: 10.5005/jp-journals-10071-23836.
3
Delayed Neurological Manifestation in Krait Bites Despite Anti-snake Venom Therapy.尽管进行了抗蛇毒血清治疗,银环蛇咬伤后仍出现延迟性神经表现。
Cureus. 2022 Oct 2;14(10):e29849. doi: 10.7759/cureus.29849. eCollection 2022 Oct.
4
Krait bite requiring high dose antivenom: a case report.需要高剂量抗蛇毒血清治疗的金环蛇咬伤:一例报告
Southeast Asian J Trop Med Public Health. 2002 Mar;33(1):170-1.
5
Hump-Nosed Pit Viper Envenomation in Western Coastal India: A Case Series.印度西部沿海的尖吻蝮蛇咬伤:病例系列。
Wilderness Environ Med. 2022 Dec;33(4):399-405. doi: 10.1016/j.wem.2022.08.006. Epub 2022 Oct 11.
6
Identification of poorly immunodepleted phospholipase A (PLA) proteins of Bungarus fasciatus venom from Assam, India and evaluation of Indian polyvalent antivenom using third-generation antivenomics.印度阿萨姆邦银环蛇毒液中免疫耗竭不佳的磷脂酶A(PLA)蛋白的鉴定以及使用第三代抗蛇毒血清组学评估印度多价抗蛇毒血清
Toxicon. 2024 Feb 23;239:107617. doi: 10.1016/j.toxicon.2024.107617. Epub 2024 Jan 12.
7
Snake Venom-specific Phospholipase A2: A Diagnostic Marker for the Management of Snakebite Cases.蛇毒特异性磷脂酶A2:蛇咬伤病例管理的诊断标志物。
Indian J Crit Care Med. 2022 Dec;26(12):1259-1266. doi: 10.5005/jp-journals-10071-24362.
8
Severe hypertension in elapid envenomation.眼镜蛇科蛇咬伤所致的严重高血压。
J Cardiovasc Dis Res. 2013 Mar;4(1):65-7. doi: 10.1016/j.jcdr.2013.02.008. Epub 2013 Feb 27.
9
Snake Bite Envenomation in a Tertiary Care Centre.三级医疗中心的蛇咬伤中毒情况
J Assoc Physicians India. 2018 Mar;66(3):55-9.
10
Cross neutralization of Afro-Asian cobra and Asian krait venoms by a Thai polyvalent snake antivenom (Neuro Polyvalent Snake Antivenom).泰国多价蛇毒血清对非亚眼镜蛇和亚洲金环蛇毒素的交叉中和作用(神经多价蛇毒血清)。
PLoS Negl Trop Dis. 2012;6(6):e1672. doi: 10.1371/journal.pntd.0001672. Epub 2012 Jun 5.

本文引用的文献

1
Ultrasound-guided selective peripheral nerve block for the snakebite pain management in the emergency department: Our experience.超声引导下选择性周围神经阻滞用于急诊科蛇咬伤疼痛管理:我们的经验。
Turk J Emerg Med. 2023 Jan 2;24(2):122-125. doi: 10.4103/2452-2473.366855. eCollection 2024 Apr-Jun.
2
Pattern of injuries due to wild animal attack among patients presenting to the emergency department: A retrospective observational study.因野生动物袭击而到急诊科就诊的患者的损伤模式:一项回顾性观察研究。
Chin J Traumatol. 2021 Nov;24(6):383-388. doi: 10.1016/j.cjtee.2021.09.004. Epub 2021 Sep 20.
3
Effect of Indian Polyvalent Antivenom in the Prevention and Reversal of Local Myotoxicity Induced by Common Cobra () Venom from Sri Lanka In Vitro.
印度多价抗蛇毒血清对预防和逆转斯里兰卡眼镜蛇毒液体外诱导的局部肌毒性的作用。
Toxins (Basel). 2021 Apr 26;13(5):308. doi: 10.3390/toxins13050308.
4
Trends in snakebite deaths in India from 2000 to 2019 in a nationally representative mortality study.2000 年至 2019 年印度全国代表性死亡率研究中蛇咬伤死亡趋势。
Elife. 2020 Jul 7;9:e54076. doi: 10.7554/eLife.54076.
5
Incidence of serum sickness after the administration of Australian snake antivenom (ASP-22).注射澳大利亚蛇毒抗毒素(ASP - 22)后血清病的发病率。
Clin Toxicol (Phila). 2016;54(1):27-33. doi: 10.3109/15563650.2015.1101771. Epub 2015 Oct 22.
6
Adverse reactions to snake antivenom, and their prevention and treatment.蛇抗毒血清的不良反应及其预防和治疗。
Br J Clin Pharmacol. 2016 Mar;81(3):446-52. doi: 10.1111/bcp.12739. Epub 2015 Sep 16.
7
Adverse drug reaction profile of anti-snake venom in a rural tertiary care teaching hospital.农村三级护理教学医院中抗蛇毒血清的药物不良反应概况
J Young Pharm. 2013 Jun;5(2):41-5. doi: 10.1016/j.jyp.2013.02.003. Epub 2013 Apr 2.
8
Pathogenic mechanisms underlying adverse reactions induced by intravenous administration of snake antivenoms.静脉注射蛇抗蛇毒血清引起不良反应的发病机制。
Toxicon. 2013 Dec 15;76:63-76. doi: 10.1016/j.toxicon.2013.09.010. Epub 2013 Sep 20.
9
Antivenin-related serum sickness.抗蛇毒血清相关血清病。
J Chin Med Assoc. 2010 Oct;73(10):540-2. doi: 10.1016/S1726-4901(10)70117-9.
10
Short-term outcomes after Fab antivenom therapy for severe crotaline snakebite.蛇伤抗蛇毒血清 Fab 治疗严重响尾蛇咬伤的短期结局。
Ann Emerg Med. 2011 Feb;57(2):128-137.e3. doi: 10.1016/j.annemergmed.2010.06.550. Epub 2010 Oct 16.