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印度一名接受多价抗蛇毒血清治疗的患者在被银环蛇咬伤后出现血清病的罕见表现:病例介绍与挑战

A rare manifestation of serum sickness after common krait envenomation in a patient treated with polyvalent anti-snake venom in India: Presentation and challenges.

作者信息

Guru Satyabrata, Bellapukonda Snigda, Mohanty Chitta R, Radhakrishnan Rakesh V, Gupta Anju

机构信息

Department of Trauma and Emergency, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.

Department of Anaesthesiology, Basavatarakam Indo-American Cancer Hospital and Research Institute, Hyderabad, Telangana, India.

出版信息

J Family Med Prim Care. 2024 Jul;13(7):2792-2794. doi: 10.4103/jfmpc.jfmpc_417_23. Epub 2024 Jun 28.

Abstract

Envenomation from snakebites is a significant public health concern in the Southeast Asian region resulting in considerable mortality and morbidity. Anti-snake venom (ASV) despite being the only rescue can bring forth several acute and delayed adverse effects. Among them, serum sickness is a late manifestation after treatment with ASV that presents after 5-14 days of treatment. However, there is no specific definition to diagnose serum sickness or proven treatment. Here, we present a case of serum sickness to provide an insight into this unventured zone, briefing the presentation, treatment and probable reason for serum sickness and its prevention after common krait envenomation and treatment with polyvalent ASV in India.

摘要

蛇咬伤中毒是东南亚地区一个重大的公共卫生问题,会导致相当高的死亡率和发病率。抗蛇毒血清(ASV)尽管是唯一的救治手段,但也会引发多种急性和迟发性不良反应。其中,血清病是使用ASV治疗后的一种晚期表现,在治疗5 - 14天后出现。然而,目前尚无诊断血清病的具体定义或经过验证的治疗方法。在此,我们报告一例血清病病例,以深入了解这一未知领域,介绍印度普通眼镜蛇咬伤并使用多价ASV治疗后血清病的表现、治疗、可能原因及其预防。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a19/11272001/f23b5d05d545/JFMPC-13-2792-g001.jpg

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